CAS 23052-81-5
:(2S)-2-Amino-4-phosphonobutanoic acid
Description:
(2S)-2-Amino-4-phosphonobutanoic acid, commonly referred to as APB, is a synthetic amino acid and a phosphonic acid derivative. It is characterized by the presence of an amino group (-NH2), a carboxylic acid group (-COOH), and a phosphonate group (-PO3H2) attached to a four-carbon backbone. This compound is known for its role as a selective agonist for certain glutamate receptors, particularly the metabotropic glutamate receptor subtype 2 (mGluR2), making it of interest in neuropharmacology and research related to neurological disorders. APB is typically a white crystalline solid and is soluble in water, which facilitates its use in biological studies. Its stereochemistry, indicated by the (2S) designation, is crucial for its biological activity, as the configuration can significantly influence receptor binding and activity. Overall, (2S)-2-Amino-4-phosphonobutanoic acid serves as a valuable tool in the study of glutamatergic signaling and has potential therapeutic implications.
Formula:C4H10NO5P
InChI:InChI=1/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
InChI key:InChIKey=DDOQBQRIEWHWBT-VKHMYHEASA-N
SMILES:C([C@@H](C(O)=O)N)CP(=O)(O)O
Synonyms:- L-2-Amino-4-phosphonobutyric acid
- Butanoic acid, 2-amino-4-phosphono-, (2S)-
- Butyric acid, 2-amino-4-phosphono-, L-
- (2S)-2-Amino-4-phosphonobutanoic acid
- Butanoic acid, 2-amino-4-phosphono-, (S)-
- L(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID 97%
- 2-ammonio-4-phosphonatobutanoate
- Anti-GDF5 (C-terminal) antibody produced in rabbit
- L-(+)-2-Amino-4-phosphonobutyric Acid - CAS 23052-81-5 - Calbiochem
- L(+)-2-AMINO-4-PHOSPHONOBUTANOIC ACID
- L-(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID (L-AP4)
- L(+)-2-Amino-4-phosphonobutyric acid,97%
- SYNS2
- (2S)-2-Amino-4-phosphonobutyric acid
- BMP-14 (GDF-5/CDMP-1) human
- GDF-5 human
- L(+)-2-Amino-4-phosphonobutanoic acid (L-AP4)
- GDF-5 mouse
- BMP-14/ CDMP-1
- (S)-4-Phosphono-2-aminobutanoic acid
- (S)-2-aMino-4-phosphonobutanoic acid
- L-AP4
- CDMP1
- L-APB
- (S)-4-Phosphono-2-aminobutyric acid
- See more synonyms
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Found 7 products.
(S)-(+)-2-Amino-4-phosphonobutyric acid, 97%
CAS:<p>A NMDA agonist</p>Formula:C4H8NO5PPurity:97%Color and Shape:PowderMolecular weight:181.09Butanoic acid, 2-amino-4-phosphono-, (2S)-
CAS:Formula:C4H10NO5PPurity:99%Color and Shape:SolidMolecular weight:183.0997L-(+)-2-Amino-4-phosphonobutyric acid
CAS:<p>M01257 - L-(+)-2-Amino-4-phosphonobutyric acid</p>Formula:C4H10NO5PPurity:99%Color and Shape:SolidMolecular weight:183.1L(+)-2-Amino-4-phosphonobutanoic Acid (L-AP4)
CAS:Controlled ProductFormula:C4H10NO5PColor and Shape:NeatMolecular weight:183.1L-AP4
CAS:<p>Inhibitor of mGluR4 receptors</p>Formula:C4H10NO5PPurity:Min. 95%Color and Shape:PowderMolecular weight:183.1 g/molL-AP4
CAS:<p>L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).</p>Formula:C4H10NO5PPurity:98%Color and Shape:White To Off-White Crystalline PowderMolecular weight:183.1






