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CAS 2305415-90-9

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7'-t-Butyldimethylsilyloxy-N-trityl-morpholino guanine

Description:
7'-t-Butyldimethylsilyloxy-N-trityl-morpholino guanine is a modified nucleoside derivative that features a morpholino ring, which enhances its stability and binding affinity in biological systems. The presence of a t-butyldimethylsilyloxy group contributes to its lipophilicity, facilitating cellular uptake, while the N-trityl group provides steric protection and enhances solubility. This compound is typically used in nucleic acid research and therapeutic applications, particularly in the development of antisense oligonucleotides and RNA interference technologies. Its structural modifications allow for improved resistance to nucleases, making it a valuable tool in gene regulation studies. The compound's unique characteristics, including its ability to form stable complexes with complementary nucleic acids, make it an important candidate in the field of molecular biology and drug design. Overall, 7'-t-Butyldimethylsilyloxy-N-trityl-morpholino guanine exemplifies the innovative approaches in synthetic chemistry aimed at enhancing the efficacy of nucleic acid-based therapies.
Formula:C35H42N6O3Si
Synonyms:
  • 7’-t-Butyldimethylsilyloxy-N-trityl-morpholinoguanine
  • 6H-Purin-6-one, 2-amino-9-[(2R,6S)-6-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-(triphenylmethyl)-2-morpholinyl]-1,9-dihydro-
  • 7'-t-Butyldimethylsilyloxy-N-trityl-morpholino guanine
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