CAS 230615-23-3

Varenicline hydrochloride

Description:

Varenicline hydrochloride is a prescription medication primarily used as an aid in smoking cessation. It acts as a partial agonist at nicotinic acetylcholine receptors, which helps to reduce withdrawal symptoms and cravings associated with nicotine addiction. The chemical formula for varenicline hydrochloride is C13H13ClN2, and it has a molecular weight of approximately 240.71 g/mol. This compound is typically administered orally and is known for its efficacy in helping individuals quit smoking by mimicking the effects of nicotine while simultaneously blocking nicotine from attaching to receptors in the brain. Varenicline hydrochloride is characterized by its relatively high solubility in water, which facilitates its absorption in the gastrointestinal tract. Common side effects may include nausea, insomnia, and vivid dreams, and it is important for users to be monitored for any psychiatric symptoms. Overall, varenicline hydrochloride represents a significant advancement in pharmacotherapy for smoking cessation, contributing to public health efforts aimed at reducing tobacco dependence.

Formula: C₁₃H₁₃N₃HCl

Synonyms:

• 6,7,8,9-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine hydrochloride
• 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 6,7,8,9-tetrahydro-, monohydrochloride

CAS: 230615-23-3

Formula: C₁₃H₁₄ClN₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 247.7234

Ref: IN-DA00BFMI

7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline hydrochloride

CAS: 230615-23-3

7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline hydrochloride

Purity: 99%

Molecular weight: 247.73g/mol

Ref: 54-OR1074607

Varenicline Hydrochloride

CAS: 230615-23-3

Varenicline Hydrochloride (CP 526555) is an orally active partial agonist of the α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM).

Formula: C₁₃H₁₄ClN₃

Purity: 99.854%

Color and Shape: Solid

Molecular weight: 247.72

Ref: TM-T23502

Varenicline Hydrochloride

Controlled Product

CAS: 230615-23-3

Formula: C₁₃H₁₃N₃·2ClH

Color and Shape: Neat

Molecular weight: 284.184

Ref: TR-V215640

Varenicline hydrochloride

CAS: 230615-23-3

Varenicline hydrochloride is a nicotinic receptor agonist that is used to treat bowel disease. It is available in the form of solid dispersions and orally as tablets. Varenicline hydrochloride prevents acetylcholine from binding to its receptors, which leads to relief of symptoms such as abdominal pain, constipation, and diarrhea. Varenicline hydrochloride has been shown to increase the level of dopamine in the striatum by acting on α7 nicotinic acetylcholine receptors. It also has been shown to have an effect on locomotor activity and inflammatory bowel disease in rats.

Formula: C₁₃H₁₄ClN₃

Purity: Min. 95%

Molecular weight: 247.72 g/mol

Ref: 3D-FV152325