CAS 23092-17-3

Halazepam

Description:

Halazepam is a benzodiazepine derivative primarily used for its anxiolytic properties. It acts on the central nervous system by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to sedative, anxiolytic, muscle relaxant, and anticonvulsant effects. Halazepam is characterized by its relatively long half-life, which allows for sustained therapeutic effects, making it suitable for the management of anxiety disorders. The substance is typically administered orally and is known for its potential side effects, which may include drowsiness, dizziness, and cognitive impairment. As with other benzodiazepines, there is a risk of dependence and withdrawal symptoms with prolonged use. Halazepam is classified as a controlled substance in many jurisdictions due to its potential for abuse. Its chemical structure includes a diazepine ring, contributing to its pharmacological activity. Overall, Halazepam is an important medication in the treatment of anxiety, but it must be used with caution under medical supervision.

Formula: C₁₇H₁₂ClF₃N₂O

InChI: InChI=1S/C17H12ClF3N2O/c18-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)22-9-15(24)23(14)10-17(19,20)21/h1-8H,9-10H2

InChI key: InChIKey=WYCLKVQLVUQKNZ-UHFFFAOYSA-N

SMILES: C(C(F)(F)F)N1C=2C(C(=NCC1=O)C3=CC=CC=C3)=CC(Cl)=CC2

Synonyms:

• 7-Chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one
• 7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
• 7-Chloro-1-(2,2,2-trifluoroethyl)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• 7-Chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-1H-1,4-benzodiazepin-2(3H)-one
• Halazepam
• Paxipam
• Sch 12041
• Schering 12041
• 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-

Halazepam

Controlled Product

CAS: 23092-17-3

Applications A benzodiazepine derivative that possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a precursor to Desmethyldiazepam (D291595) and is equal to or more effective than Diazepam (D416855) with a lower frequency of side effects.Controlled Substance.
References Fann, W.E. et al.: Pharmacother., 2, 72 (1982); Greenblatt, D.J. et al.: Lancet, 1, 1358 (1982);

Formula: C₁₇H₁₂ClF₃N₂O

Color and Shape: Neat

Molecular weight: 352.74

Ref: TR-H101500

Halazepam (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 23092-17-3

Formula: C₁₇H₁₂ClF₃N₂O

Color and Shape: Single Solution

Molecular weight: 352.74

Ref: TR-KIT4845