CAS 23094-69-1

Corilagin

Description:

Corilagin is a naturally occurring polyphenolic compound classified as a tannin, primarily found in various plants, particularly in the family of Phyllanthaceae. It is known for its antioxidant, anti-inflammatory, and antimicrobial properties, making it of interest in both pharmacological and nutritional research. Corilagin exhibits a complex structure, characterized by multiple hydroxyl groups that contribute to its reactivity and biological activity. The compound has been studied for its potential therapeutic effects, including its role in modulating metabolic pathways and its protective effects against oxidative stress. Additionally, corilagin has shown promise in various in vitro and in vivo studies for its ability to influence cell signaling pathways, which may have implications for treating diseases such as cancer and diabetes. Its solubility in water and organic solvents varies, which can affect its bioavailability and efficacy in different applications. Overall, corilagin represents a significant area of interest in natural product chemistry and pharmacology due to its diverse biological activities.

Formula: C₂₇H₂₂O₁₈

InChI: InChI=1S/C27H22O18/c28-9-1-6(2-10(29)16(9)32)24(39)45-27-22(38)23-19(35)13(43-27)5-42-25(40)7-3-11(30)17(33)20(36)14(7)15-8(26(41)44-23)4-12(31)18(34)21(15)37/h1-4,13,19,22-23,27-38H,5H2

InChI key: InChIKey=TUSDEZXZIZRFGC-UHFFFAOYSA-N

SMILES: OC1=C2C=3C(=CC(O)=C(O)C3O)C(=O)OCC4C(O)C(OC(=O)C2=CC(O)=C1O)C(O)C(OC(=O)C5=CC(O)=C(O)C(O)=C5)O4

Synonyms:

• (8R,10S,11R,12S,19R)-1,2,3,11,16,17,18,19-octahydroxy-5,14-dioxo-5,7,8,11,12,14-hexahydro-10H-8,12-methanodibenzo[j,l][1,4,8]trioxacyclotetradecin-10-yl 3,4,5-trihydroxybenzoate
• 1,2,3,11,16,17,18,19-octahydroxy-5,14-dioxo-5,7,8,11,12,14-hexahydro-10H-8,12-methanodibenzo[j,l][1,4,8]trioxacyclotetradecin-10-yl 3,4,5-trihydroxybenzoate
• 8,12-Methano-10H-dibenzo[j,l][1,4,8]trioxacyclotetradecin, β-<span class="text-smallcaps">D</span>-glucopyranose deriv.
• Corillagin
• Glucopyranose, cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxydiphenate) 1-gallate, β-<span class="text-smallcaps">D</span>-
• beta-D-Glucopyranose, cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy(1,1'-biphenyl)-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), (R)-
• β-<span class="text-smallcaps">D</span>-Glucopyranose, cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), (R)-
• β-<span class="text-smallcaps">D</span>-Glucopyranose, cyclic 3,6-[(1R)-4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate] 1-(3,4,5-trihydroxybenzoate)
• β-D-Glucopyranose, cyclic 3,6-[(1R)-4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate] 1-(3,4,5-trihydroxybenzoate)
• 8,12-Methano-10H-dibenzo[j,l][1,4,8]trioxacyclotetradecin, β-D-glucopyranose deriv.
• β-D-Glucopyranose, cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), (R)-
• Glucopyranose, cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxydiphenate) 1-gallate, β-D-

β-D-Glucopyranose, cyclic 3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1-(3,4,5-trihydroxybenzoate)

CAS: 23094-69-1

Formula: C₂₇H₂₂O₁₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 634.4528

Ref: IN-DA002M6S

Corilagin

CAS: 23094-69-1

Corilagin

Purity: ≥98%

Molecular weight: 634.45g/mol

Ref: 54-BUP06428

Corilagin

CAS: 23094-69-1

Corilagin

Purity: 98%

Molecular weight: 634.45g/mol

Ref: 54-OR1024248

Corilagin

CAS: 23094-69-1

Corilagin has antitumour, anti-inflammatory, antioxidant, antifibrotics, antiviral, antibacterial, hepatoprotective, antiatherogenic, and antihypertensive activities. Corilagin reduces the cytotoxicity induced by EV71 or CA16 on Vero cells with and IC50 value of 5.6 and 32.33 μg/mL, respectively; it shows the potential to protect against HSV-1-induced encephalitis, and the beneficial effects may be mediated by inhibiting TLR2 signaling pathways. Corilagin attenuates bleomycin-induced epithelial injury and fibrosis via inactivation of oxidative stress, proinflammatory cytokine release and NF-κB and TGF-β1 signaling; it suppresses the activity of beta-lactamase to some extent.

Formula: C₂₇H₂₂O₁₈

Purity: 95%~99%

Molecular weight: 634.455

Ref: BP-BP0393

Corilagin

CAS: 23094-69-1

Formula: C₂₇H₂₂O₁₈

Molecular weight: 634.46

Ref: 4Z-C-495001

Corilagin

CAS: 23094-69-1

Corilagin has anti-inflammatory activity.

Formula: C₂₇H₂₂O₁₈

Purity: 99.54% - 99.95%

Color and Shape: Off-White Solid

Molecular weight: 634.45

Ref: TM-T3795

Corilagin

CAS: 23094-69-1

Formula: C₂₇H₂₂O₁₈

Purity: ≥ 98.0%

Color and Shape: White to off-white, light yellow or light brown powder

Molecular weight: 634.46

Ref: 7W-GC8106

Corilagin

CAS: 23094-69-1

Natural glycoside

Formula: C₂₇H₂₂O₁₈

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 634.46

Ref: 5G-80390

Corilagin

Controlled Product

CAS: 23094-69-1

Stability Hygroscopic
Applications Thrombolytic.
References Shen, Z-Q., et al.: Planta Med., 69, 1109 (2003),

Formula: C₂₇H₂₂O₁₈

Color and Shape: Neat

Molecular weight: 634.45

Ref: TR-C695400

Corilagin

Controlled Product

CAS: 23094-69-1

Corilagin is a natural compound that has been shown to inhibit cancer cell growth and induce apoptosis. Corilagin inhibits the production of anion radicals, which are reactive species that contribute to oxidative stress and inflammation. Corilagin also has an anti-inflammatory effect by inhibiting the production of pro-inflammatory cytokines. In addition, corilagin induces autophagy, a process where cells degrade their own components through the lysosomal machinery in order to generate energy and eliminate toxic substances. Corilagin is also able to reduce cellular transformation through its ability to inhibit secretase activity.

Formula: C₂₇H₂₂O₁₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 634.45 g/mol

Ref: 3D-MC11453