CAS 230961-21-4

(3R)-3-{[(2S)-1-{[(1S)-2-methoxy-1-phenylethyl]amino}-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}-6-(2-methylbiphenyl-4-yl)hexanoic acid

Description:

The chemical substance with the name "(3R)-3-{[(2S)-1-{[(1S)-2-methoxy-1-phenylethyl]amino}-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}-6-(2-methylbiphenyl-4-yl)hexanoic acid" and CAS number "230961-21-4" is a complex organic compound characterized by its chiral centers and multiple functional groups. It features a hexanoic acid backbone, which is modified with a carbamoyl group and a substituted amino acid structure. The presence of a methoxy group and a phenyl ring contributes to its potential biological activity, possibly influencing its interaction with biological targets. The stereochemistry indicated by the (R) and (S) designations suggests that the compound may exhibit specific pharmacological properties, as chirality can significantly affect the behavior of molecules in biological systems. Additionally, the presence of bulky substituents, such as the 2-methylbiphenyl group, may impact the compound's solubility, stability, and overall reactivity. Such characteristics make it a candidate for further investigation in medicinal chemistry and drug development.

Formula: C₃₅H₄₄N₂O₅

InChI: InChI=1/C35H44N2O5/c1-24-21-25(19-20-29(24)26-14-8-6-9-15-26)13-12-18-28(22-31(38)39)33(40)37-32(35(2,3)4)34(41)36-30(23-42-5)27-16-10-7-11-17-27/h6-11,14-17,19-21,28,30,32H,12-13,18,22-23H2,1-5H3,(H,36,41)(H,37,40)(H,38,39)/t28-,30-,32-/m1/s1

SMILES: Cc1cc(CCC[C@H](CC(=O)O)C(=N[C@H](C(=N[C@H](COC)c2ccccc2)O)C(C)(C)C)O)ccc1c1ccccc1

[1,1'-Biphenyl]-4-hexanoic acid, β-[[[(1S)-1-[[[(1S)-2-methoxy-1-phenylethyl]amino]carbonyl]-2,2-dimethylpropyl]amino]carbonyl]-2-methyl-, (βR)-

CAS: 230961-21-4

Formula: C₃₅H₄₄N₂O₅

Purity: 96.70%

Color and Shape: Solid

Molecular weight: 572.7343

Ref: IN-DA002M6D

UK 370106

Controlled Product

CAS: 230961-21-4

Formula: C₃₅H₄₄N₂O₅

Color and Shape: Neat

Molecular weight: 572.73426

Ref: TR-U700620

UK 370106

CAS: 230961-21-4

UK 370106 is a matrix metalloproteinase inhibitor, which inhibits the activity of enzymes that break down collagen and other proteins in the extracellular matrix. This inhibition leads to a reduction in the production of tumor necrosis factor-α (TNF-α) and other inflammatory cytokines. UK 370106 has been shown to inhibit both proenzyme MMP-1 and active enzyme MMP-1 in cancer cell lines and monoclonal antibody-producing cells. This drug also synergistically interacts with colchicine and 5-fluorouracil, two chemotherapeutic drugs used in cancer therapy. UK 370106 also has been shown to inhibit collagen degradation by human neutrophils, thereby preventing inflammation.

Formula: C₃₅H₄₄N₂O₅

Purity: Min. 95%

Molecular weight: 572.73 g/mol

Ref: 3D-FJA96121

UK-370106

CAS: 230961-21-4

UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-

Formula: C₃₅H₄₄N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 572.73

Ref: TM-T13249