CAS 231278-20-9

N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine

Description:

N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine is a synthetic organic compound characterized by its complex molecular structure, which includes a quinazolinamine core. This compound features multiple functional groups, including a chloro group, a methoxy group, and a fluorophenyl moiety, contributing to its potential biological activity. The presence of iodine in the structure may enhance its lipophilicity and influence its interaction with biological targets. Typically, compounds of this nature are investigated for their pharmacological properties, particularly in the context of cancer research or as potential therapeutic agents due to their ability to inhibit specific enzymes or receptors. The molecular weight and solubility characteristics can vary, affecting its bioavailability and efficacy. As with many synthetic compounds, safety and toxicity profiles are essential considerations in their development and application. Overall, this compound exemplifies the complexity and diversity of modern medicinal chemistry, where structural modifications can lead to significant variations in biological activity.

Formula: C₂₁H₁₄ClFIN₃O

InChI: InChI=1S/C21H14ClFIN3O/c22-18-10-16(5-7-20(18)28-11-13-2-1-3-14(23)8-13)27-21-17-9-15(24)4-6-19(17)25-12-26-21/h1-10,12H,11H2,(H,25,26,27)

InChI key: InChIKey=UHFPFDMMKYQMLC-UHFFFAOYSA-N

SMILES: N(C=1C2=C(N=CN1)C=CC(I)=C2)C3=CC(Cl)=C(OCC4=CC(F)=CC=C4)C=C3

Synonyms:

• 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-
• 4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-iodoquinazoline
• 6-Iodo-(4-(3-Fluorobenzyloxy)-3-Chlorophenyl)-Quinazolin-4Yl)Amine
• 6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline
• Lapatinib's intermediate
• N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazoline-4-amine
• N-{3-Chloro-4-[(3-fluorophenyl)-methoxy]-phenyl}-6-iodo-4-quinazolinamine
• N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine
• N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodoquinazolin-4-amine
• [3-Chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-iodo-quinazolin-4-yl)-amine
• [3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl](6-iodoquinazolin-4-yl)amine

4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline

CAS: 231278-20-9

Formula: C₂₁H₁₄ClFIN₃O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 505.72

Ref: 3B-C2965

4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline, 97%

CAS: 231278-20-9

4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline is used as an organic chemical synthesis intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The o

Formula: C₂₁H₁₄ClFIN₃O

Purity: 97%

Molecular weight: 505.72

Ref: 02-H54229

4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-

CAS: 231278-20-9

Formula: C₂₁H₁₄ClFIN₃O

Purity: 97%

Color and Shape: Solid

Molecular weight: 505.7112

Ref: IN-DA002M91

N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine

CAS: 231278-20-9

N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine

Purity: 99%

Molecular weight: 505.72g/mol

Ref: 54-PC101733

N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine

CAS: 231278-20-9

Purity: 98%

Molecular weight: 505.7200012207031

Ref: 10-F791124

N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine

Controlled Product

CAS: 231278-20-9

Applications 3-[(4-Bromophenyl)(methyl)amino]propanoic acid (cas# 231278-20-9) is a quinazoline derivative and an aryl iodide. 3-[(4-Bromophenyl)(methyl)amino]propanoic acid has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.
References Zhang, Y.; et al.: Bioorg. Med. Chem. Lett., 27, 1584 (2017); Lin, S.; Eur. J. Med. Chem., 127, 442 (2017).

Formula: C₂₁H₁₄ClFIN₃O

Color and Shape: Neat

Molecular weight: 505.71

Ref: TR-B807825

Lapatinib Impurity 15

CAS: 231278-20-9

Formula: C₂₁H₁₄ClFIN₃O

Molecular weight: 505.72

Ref: ST-EA-CP-L46015

N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine

CAS: 231278-20-9

N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T65343 and the CAS number is 231278-20-9.

Formula: C₂₁H₁₄ClFIN₃O

Color and Shape: Solid

Molecular weight: 505.71

Ref: TM-T65343