CAS 231278-84-5

5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-Furancarboxaldehyde

Description:

The chemical substance known as 5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde, with the CAS number 231278-84-5, is a complex organic compound characterized by its multi-functional structure. It features a quinazoline core, which is a bicyclic compound known for its biological activity, particularly in medicinal chemistry. The presence of a furancarboxaldehyde moiety suggests potential reactivity due to the aldehyde functional group, which can participate in various chemical reactions, including condensation and nucleophilic addition. The compound also contains a chloro substituent and a fluorophenyl group, which may influence its pharmacological properties and interactions with biological targets. Its intricate structure indicates potential applications in drug development, particularly in targeting specific pathways or receptors in disease processes. The compound's solubility, stability, and reactivity would depend on its specific functional groups and overall molecular conformation, making it a subject of interest for further research in medicinal chemistry and related fields.

Formula: C₂₆H₁₇ClFN₃O₃

InChI: InChI=1/C26H17ClFN3O3/c27-22-12-19(5-8-25(22)33-14-16-2-1-3-18(28)10-16)31-26-21-11-17(4-7-23(21)29-15-30-26)24-9-6-20(13-32)34-24/h1-13,15H,14H2,(H,29,30,31)

SMILES: c1cc(cc(c1)F)COc1ccc(cc1Cl)Nc1c2cc(ccc2ncn1)c1ccc(C=O)o1

Synonyms:

• 5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde
• [5-[4-[4-[(3-Fluorobenzyl)oxy]-3-chloroanilino]-6-quinazolinyl]-2-furancarboxaldehyde
• 5-[4-({3-Chloro-4-[(3-Fluorobenzyl)Oxy]Phenyl}Amino)Quinazolin-6-Yl]Furan-2-Carbaldehyde
• 5-(4-(3-Chloro-4-((3-fluorobenzyloxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde
• Lapatinib Intermediate 3
• 5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy] phenyl]amino]-6-quinazolinyl]-2-Furancarboxaldehyde

2-Furancarboxaldehyde, 5-[4-[[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-

CAS: 231278-84-5

Formula: C₂₆H₁₇ClFN₃O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 473.8829

Ref: IN-DA002M90

5-[4-[[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]amino]quinazolin-6-yl]furan-2-carboxaldehyde

CAS: 231278-84-5

5-[4-[[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]amino]quinazolin-6-yl]furan-2-carboxaldehyde

Purity: 99%

Molecular weight: 473.89g/mol

Ref: 54-PC99876

Lapatinib Impurity 9

CAS: 231278-84-5

Formula: C₂₆H₁₇ClFN₃O₃

Color and Shape: Yellow Solid

Molecular weight: 473.89

Ref: 4Z-L-2510

5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde

CAS: 231278-84-5

Purity: 97.0%

Molecular weight: 473.8900146484375

Ref: 10-F545007

5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino) quinazolin-6-yl)furan-2-carbaldehyde

CAS: 231278-84-5

5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde is a heterocyclic compound that has been used to study protein tyrosine kinase activity. This drug binds to the active site of the enzyme and inhibits its function by forming an irreversible covalent bond with the enzyme's reactive cysteine residue, which prevents the transfer of phosphate groups from ATP to the substrate (tyrosine).

Formula: C₂₆H₁₇ClFN₃O₃

Purity: Min. 95%

Molecular weight: 473.88 g/mol

Ref: 3D-FC32843

5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde

Controlled Product

CAS: 231278-84-5

Formula: C₂₆H₁₇ClFN₃O₃

Color and Shape: Neat

Molecular weight: 473.88

Ref: TR-C366385

Lapatinib Impurity 5

CAS: 231278-84-5

Formula: C₂₆H₁₇ClFN₃O₃

Molecular weight: 473.89

Ref: ST-EA-CP-L46007