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CAS 2315-02-8

:

oxymetazoline hydrochloride

Description:
Oxymetazoline hydrochloride is a sympathomimetic agent primarily used as a topical decongestant. It belongs to the imidazoline class of compounds and is commonly found in nasal sprays and eye drops. The substance works by stimulating alpha-adrenergic receptors, leading to vasoconstriction of the nasal mucosa, thereby reducing swelling and congestion. Oxymetazoline is characterized by its relatively long duration of action, making it effective for relieving nasal congestion due to colds, allergies, or sinusitis. It is typically administered in a racemic mixture and is known for its rapid onset of action. While generally safe for short-term use, prolonged application can lead to rebound congestion, a condition known as rhinitis medicamentosa. The compound is soluble in water and has a pH range that is compatible with mucosal tissues, which enhances its usability in pharmaceutical formulations. As with any medication, it is important to follow dosing guidelines to minimize potential side effects and avoid complications associated with overuse.
Formula:C16H24N2O·ClH
InChI:InChI=1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
InChI key:InChIKey=BEEDODBODQVSIM-UHFFFAOYSA-N
SMILES:C(C1=C(C)C(O)=C(C(C)(C)C)C=C1C)C=2NCCN2.Cl
Synonyms:
  • 2,6-Dimethyl-4-tertiarybutyl-3-hydroxyphenyl)methylimidazoline hydrochloride
  • 2-(4-tert-Butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazolinium chloride
  • 2-(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazol-3-ium
  • 4-Way Nasal 12 Hour Spray
  • 4-Way Nasal Spray
  • 6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol hydrochloride
  • Afrazine
  • Afrin
  • Afrin hydrochloride
  • Allerest 12 Hour Nasal Spray
  • See more synonyms
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