CAS 23198-01-8: 5-Methyluridine 5′-triphosphate

Description: 5-Methyluridine 5′-triphosphate (m^5UTP) is a modified nucleotide that plays a significant role in various biochemical processes, particularly in RNA synthesis and modification. It is a derivative of uridine triphosphate (UTP), where a methyl group is added to the 5-position of the uracil base. This modification can influence the stability and functionality of RNA molecules, making m^5UTP important in the context of gene expression and regulation. The triphosphate group is crucial for its role as a substrate in RNA polymerization, providing the necessary energy for the formation of phosphodiester bonds during RNA synthesis. Additionally, m^5UTP can be involved in post-transcriptional modifications, impacting RNA structure and function. Its unique characteristics, such as altered base pairing and enhanced resistance to degradation, make it a valuable tool in molecular biology and biochemistry, particularly in studies involving RNA dynamics and the development of RNA-based therapeutics.

Formula: C₁₀H₁₇N₂O₁₅P₃

InChI: InChI=1S/C10H17N2O15P3/c1-4-2-12(10(16)11-8(4)15)9-7(14)6(13)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5-7,9,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t5-,6-,7-,9-/m1/s1

InChI key: InChIKey=RZCIEJXAILMSQK-JXOAFFINSA-N

SMILES: O=C1NC(=O)N(C=C1C)C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O

Synonyms:

• Uridine, 5-methyl-, 5′-triphosphate
• Uridine 5′-(tetrahydrogen triphosphate), 5-methyl-
• 5-Methyluridine 5′-(tetrahydrogen triphosphate)
• Uridine, 5-methyl-, 5′-(tetrahydrogen triphosphate)
• Ribothymidine 5′-triphosphate

5-Methyluridine-5'-triphosphate Sodium Salt (ca. 100mM in Water) [for transcription] [for Molecular Biology]

CAS: 23198-01-8

• Formula: C₁₀H₁₇N₂O₁₅P₃·xNa
• Purity: min. 98.0 area%(HPLC)
• Color and Shape: Colorless to Light yellow clear liquid