
CAS 2319922-08-0
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Found 2 products.
ML 218 hydrochloride
CAS:<p>ML 218 hydrochloride is a calcium-channel blocker that inhibits the influx of extracellular calcium into cells. ML 218 hydrochloride has been shown to be effective in the treatment of conditions such as brain cell dysregulation and sclerosis, where there is an increased concentration of sulfate ions. This drug binds to sulfated glycosaminoglycans, which are found on the surface of cells, blocking the entry of calcium ions into cells. It also inhibits the release of calcium from intracellular stores by binding to receptors on the cell membrane. ML 218 hydrochloride has a multistep mechanism: it blocks influx from outside the cell and releases calcium from inside the cell.</p>Formula:C19H27Cl3N2OPurity:Min. 95%Molecular weight:405.8 g/molML218 hydrochloride
CAS:<p>ML218 hydrochloride inhibits T-type Ca2+ channels Cav3.1-3.3; most effective on Cav3.2 and Cav3.3 (IC50s: 310 nM, 270 nM).</p>Formula:C19H27Cl3N2OPurity:98%Color and Shape:SolidMolecular weight:405.79

