CAS 23210-56-2

Ifenprodil

Description:

Ifenprodil is a chemical compound primarily recognized for its role as a neuroprotective agent and its potential therapeutic applications in treating neurological disorders. It is classified as a non-competitive antagonist of the NMDA (N-methyl-D-aspartate) receptor, which plays a crucial role in synaptic plasticity and memory function. Ifenprodil exhibits selectivity for certain NMDA receptor subtypes, particularly those containing the NR2B subunit, making it of interest in research related to neurodegenerative diseases and conditions associated with excitotoxicity. The compound is typically administered in its hydrochloride salt form and is known for its ability to modulate glutamatergic neurotransmission. Additionally, Ifenprodil has been studied for its potential effects on cardiovascular health, as it may influence vascular smooth muscle function. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are important for understanding its efficacy and safety profile in clinical settings. Overall, Ifenprodil represents a significant area of interest in pharmacological research, particularly in the context of neuroprotection and related therapeutic strategies.

Formula: C₂₁H₂₇NO₂

InChI: InChI=1/2C21H27NO2.C4H6O6/c2*1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17;5-1(3(7)8)2(6)4(9)10/h2*2-10,16,18,21,23-24H,11-15H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)

InChI key: InChIKey=UYNVMODNBIQBMV-UHFFFAOYSA-N

SMILES: C(C1CCN(C(C(O)C2=CC=C(O)C=C2)C)CC1)C3=CC=CC=C3

Synonyms:

• 1-Methyl-2-hydroxy-2-(4-hydroxyphenyl)ethyl-1-(4-benzylpiperidine)
• 1-Piperidineethanol, 4-benzyl-α-(p-hydroxyphenyl)-β-methyl-
• 1-Piperidineethanol, Alpha-(4-Hydroxyphenyl)-Beta-Methyl-4-(Phenylmethyl)-
• 1-Piperidineethanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-
• 2-(4-Benzylpiperidino)-1-(1-hydroxyphenyl)-1-propanol
• 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol
• 23210-56-2
• 4-Benzyl-a-(p-hydroxyphenyl)-b-methyl-1-piperidineethanol
• 4-[2-(4-Benzyl-1-pipéridinyl)-1-hydroxypropyl]phénol
• 4-[2-(4-Benzylpiperidin-1-Yl)-1-Hydroxypropyl]Phenol 2,3-Dihydroxybutanedioate (2:1)
• 4-[2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl]phenol
• 66157-43-5
• Rc 61-91
• α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidineethanol
• Ifenprodil
• (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemi-(DL)-tartrate
• (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanolhemitartrate
• 4-benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethano
• 1-(4-Hydroxyphenyl)-2-(4-benzylpiperidino)-1-propanol
• alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidineethano
• 4-[2-[4-(benzyl)-1-piperidyl]-1-hydroxy-propyl]phenol
• 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol tartrate (2:1) salt
• alpha-(4-Hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidineethanol
• 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)propanol
• 4-[1-Hydroxy-2-[4-(phenylmethyl)piperidin-1-yl]propyl]phenol
• 4-benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethanol
• 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)propan-1-ol

Ifenprodil hemitartrate, 99%

CAS: 23210-56-2

NMDA receptor antagonist, acting at the polyamine site

Formula: C₂₁H₂₇NO₂·5C₄H₆O₆

Purity: 99%

Molecular weight: 400.49

Ref: 02-J60932

Ifenprodil

CAS: 23210-56-2

Ifenprodil (RC61-91) inhibits NMDA receptor subunits GluN1 & GluN2B, GIRK channels, and affects alpha1, serotonin, sigma receptors.

Formula: C₂₁H₂₇NO₂

Purity: 99.58%

Color and Shape: White Crystalline Powder

Molecular weight: 325.44

Ref: TM-T1186L

1-Piperidineethanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-

CAS: 23210-56-2

Formula: C₂₁H₂₇NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 325.44458

Ref: IN-DA002MJD

Ifenprodil

CAS: 23210-56-2

Ifenprodil

Purity: ≥98%

Molecular weight: 325.44g/mol

Ref: 54-BUP09455

Ifenprodil

CAS: 23210-56-2

Formula: C₂₁H₂₇NO₂₀·5C₄H₆O₆

Molecular weight: 400.49

Ref: 7W-GP2257

Ifenprodil

Controlled Product

CAS: 23210-56-2

Applications Ifenprodil is a NMDA receptor antagonist.
References Berger, et al.: J. Pharmacol. Exp. Ther., 289, 1584 (1999);

Formula: C₂₁H₂₇NO₂

Color and Shape: Neat

Molecular weight: 325.44

Ref: TR-I258003

Ifenprodil

Controlled Product

CAS: 23210-56-2

Ifenprodil is a selective NMDA (N-Methyl-D-aspartate) receptor antagonist, which is a synthetic compound designed to modulate glutamatergic neurotransmission. It is derived from a class of organic compounds known as phenylethanolamines. Its primary mode of action involves the inhibition of NMDA receptors containing the GluN2B subunit, which leads to a reduction in excitatory neurotransmission. This specific antagonism is crucial for modulating synaptic plasticity and protecting neural tissue from excitotoxic damage.

Formula: (C₂₁H₂₇NO₂)·C₄H₆O₆

Purity: Min. 95%

Molecular weight: 800.98 g/mol

Ref: 3D-YAA21058