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CAS 2323-36-6

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(±)-Selegiline

Description:
(±)-Selegiline, also known as L-deprenyl, is a selective monoamine oxidase B (MAO-B) inhibitor primarily used in the treatment of Parkinson's disease and major depressive disorder. It is a chiral compound, existing as a racemic mixture of its two enantiomers, which exhibit different pharmacological properties. The substance is characterized by its ability to increase the levels of dopamine in the brain by inhibiting its breakdown, thus enhancing dopaminergic activity. (±)-Selegiline is typically administered orally and is known for its neuroprotective effects, potentially delaying the progression of neurodegenerative diseases. In addition to its therapeutic uses, it has been studied for its potential in treating cognitive decline and as an adjunct in the management of depression. The compound is generally well-tolerated, though it may interact with certain medications and dietary tyramine, necessitating caution in its use. Its chemical structure includes a phenethylamine backbone, contributing to its biological activity and interaction with neurotransmitter systems.
Formula:C13H17N
InChI:InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3
InChI key:InChIKey=MEZLKOACVSPNER-UHFFFAOYSA-N
SMILES:C(C(N(CC#C)C)C)C1=CC=CC=C1
Synonyms:
  • N,α-Dimethyl-N-2-propyn-1-ylbenzeneethanamine
  • Benzeneethanamine, N,α-dimethyl-N-2-propynyl-
  • Phenethylamine, N,α-dimethyl-N-2-propynyl-
  • Benzeneethanamine, N,α-dimethyl-N-2-propyn-1-yl-
  • Deprenyl
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