CAS 2326-26-3

(6α,11β)-21-(Acetyloxy)-6,9-difluoro-11-hydroxypregna-1,4,16-triene-3,20-dione

Description:

The chemical substance known as "(6α,11β)-21-(Acetyloxy)-6,9-difluoro-11-hydroxypregna-1,4,16-triene-3,20-dione," with the CAS number 2326-26-3, is a synthetic corticosteroid. It exhibits anti-inflammatory and immunosuppressive properties, making it useful in various medical applications, particularly in treating conditions such as asthma, allergies, and autoimmune disorders. The structure of this compound features a steroid backbone with specific modifications, including fluorine substitutions and an acetoxy group, which enhance its biological activity and stability. The presence of hydroxyl groups contributes to its solubility and interaction with biological receptors. As a corticosteroid, it functions by modulating gene expression and inhibiting the release of inflammatory mediators, thereby reducing inflammation and immune responses. Its pharmacokinetics typically involve metabolism in the liver and excretion via the kidneys. Safety and efficacy profiles are established through clinical studies, and like other corticosteroids, it may have side effects, necessitating careful monitoring during therapeutic use.

Formula: C₂₃H₂₆F₂O₅

InChI: InChI=1/C23H26F2O5/c1-12(26)30-11-19(28)15-5-4-14-16-9-18(24)17-8-13(27)6-7-22(17,3)23(16,25)20(29)10-21(14,15)2/h5-8,14,16,18,20,29H,4,9-11H2,1-3H3/t14-,16-,18-,20-,21-,22-,23-/m0/s1

InChI key: InChIKey=YXASFOVLXBFEEU-LKVAYOKUSA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)C(C(COC(C)=O)=O)=CC3)[H])(C[C@H](F)C=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• (6Alpha,11Beta)-6,9-Difluoro-11-Hydroxy-3,20-Dioxopregna-1,4,16-Trien-21-Yl Acetate
• (6α,11β)-21-(Acetyloxy)-6,9-difluoro-11-hydroxypregna-1,4,16-triene-3,20-dione
• 219-040-7
• Pregna-1,4,16-triene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-, (6α,11β)-
• Pregna-1,4,16-triene-3,20-dione, 6α,9-difluoro-11β,21-dihydroxy-, 21-acetate
• "6a,9-Difluoro-11,21-dihydroxy-pregna-1,4,16-triene-3,20-dione"
• 6,9-Difluoropregna-1,4,16-triene-11,21-diol-3,20-dione 21-acetate
• (6α,11β)-6,9-Difluoro-11-hydroxy-3,20-dioxopregna-1,4,16-trien-21 -yl acetate
• DifluprednateImpurity1/2-((6S,8S,9R,10S,11S,13S,14S)-6,9-Difluoro-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethylacetate
• Einecs 219-040-7
• 21-Acetyloxy-6α,9-difluoro-11β-hydroxypregna-1,4,16-triene-3,20-dione
• 6,9-Difluoro-11,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
• Difluprednate Impurity 16
• 6alpha,9-difluoro-11beta,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate

Difluprednate Impurity 16

CAS: 2326-26-3

Formula: C₂₃H₂₆F₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 420.45

Ref: 4Z-D-125021

6α,9-Difluoro-11β,21-dihydroxy-pregna-1,4,16-triene-3,20-dione

Controlled Product

CAS: 2326-26-3

Applications Steroidal isoxazolidine derivative used in the preparation of anti-inflammatory and antiallergic agents. A glucocorticoid.

Formula: C₂₃H₂₆F₂O₅

Color and Shape: Neat

Molecular weight: 420.45

Ref: TR-D443740

(6a,11b)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-Pregna-1,4,16-triene-3,20-dione

Controlled Product

CAS: 2326-26-3

Please enquire for more information about (6a,11b)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-Pregna-1,4,16-triene-3,20-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₃H₂₆F₂O₅

Purity: Min. 95%

Molecular weight: 420.45 g/mol

Ref: 3D-FA100437

Difluprednate Impurity 13

CAS: 2326-26-3

Formula: C₂₃H₂₆F₂O₅

Molecular weight: 420.5

Ref: ST-EA-CP-D100009