CAS 23278-88-8

4-(dimethylamino)-2,2-diphenylbutanenitrile

Description:

4-(Dimethylamino)-2,2-diphenylbutanenitrile, with the CAS number 23278-88-8, is an organic compound characterized by its complex structure, which includes a butanenitrile backbone substituted with a dimethylamino group and two phenyl groups. This compound typically appears as a solid at room temperature and is known for its potential applications in various fields, including pharmaceuticals and organic synthesis. The presence of the dimethylamino group contributes to its basicity and can influence its reactivity, making it a useful intermediate in chemical reactions. Additionally, the phenyl groups enhance its hydrophobic characteristics, which can affect its solubility in different solvents. The nitrile functional group (-C≡N) is notable for its ability to participate in nucleophilic addition reactions, further expanding its utility in synthetic chemistry. Overall, 4-(dimethylamino)-2,2-diphenylbutanenitrile is a versatile compound with significant implications in chemical research and development.

Formula: C₁₈H₂₀N₂

InChI: InChI=1/C18H20N2/c1-20(2)14-13-18(15-19,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-12H,13-14H2,1-2H3

SMILES: CN(C)CCC(C#N)(c1ccccc1)c1ccccc1

Synonyms:

• Benzeneacetonitrile, Alpha-[2-(Dimethylamino)Ethyl]-Alpha-Phenyl-

4-(Dimethylamino)-2,2-diphenyl-butyronitrile

Controlled Product

CAS: 23278-88-8

Applications 4-(Dimethylamino)-2,2-diphenyl-butyronitrile is an intermediate used in the synthesis of Normethadone Hydrochloride (N733500), which is a desmethyl analog of Methadone (M225865). A cough suppressant. Controlled Substance.
References Eiden, F. et al.: Pharmaz. Zait., 117, 1503 (1972); Anand, D.R.: Arzneim.-Forsch., 15, 564 (1965);

Formula: C₁₈H₂₀N₂

Color and Shape: Neat

Molecular weight: 264.365

Ref: TR-D481345