CAS 23313-68-0
:Verapamil hydrochloride
Description:
Verapamil hydrochloride is a calcium channel blocker primarily used in the treatment of hypertension, angina pectoris, and certain types of arrhythmias. It is a white to off-white crystalline powder that is soluble in water and exhibits a pH range of approximately 4.5 to 7.5 when dissolved. The compound functions by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to relaxation of vascular smooth muscle and a decrease in heart rate. Its chemical formula is C27H38N2O5·HCl, and it has a molecular weight of approximately 491.08 g/mol. Verapamil hydrochloride is often administered orally or intravenously, and its pharmacokinetics include extensive hepatic metabolism and variable bioavailability. Common side effects may include dizziness, constipation, and hypotension. As with any medication, it is essential to use verapamil under medical supervision, considering potential drug interactions and contraindications.
Formula:C27H38N2O4·ClH
InChI:InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H
InChI key:InChIKey=DOQPXTMNIUCOSY-UHFFFAOYSA-N
SMILES:C(CCCN(CCC1=CC(OC)=C(OC)C=C1)C)(C(C)C)(C#N)C2=CC(OC)=C(OC)C=C2.Cl
Synonyms:- (+/-)-5-[N-(3,4-dimethoxyphenylethyl)-METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYLVALERONITRILE HYDROCHLORIDE
- 2-(3,4-Dimethoxyphenyl)-5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]-2-(propan-2-yl)pentanenitrile hydrochloride
- 2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-Dimethoxyphenyl)Ethyl](Methyl)Amino}-2-(Propan-2-Yl)Pentanenitrile Hydrochloride (1:1)
- 5-[(3,4-DIMETHOXYPHENETHYL)METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYL-VALERONITRILE HYDROCHLORIDE
- Akilen
- Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-
- Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-Benzeneacetonitrile Hydrochloride
- Anpec
- Apo-Verap
- Apoacor
- Arapamyl
- Azupamil
- Benzeneacetonitrile Hydrochloride
- Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, hydrochloride (1:1)
- Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, monohydrochloride
- Berkatens
- Calan
- Calan SR
- Calaptin
- Calaptin 240SR
- Calaptin 80
- Cardiabeltin
- Cardiagutt
- Cardibeltin
- Caveril
- Civicor
- Civicor Retard
- Coraver
- Cordilox
- Cordilox SR
- Corpamil
- Covera HS
- Dignover
- Dilacoran
- Dilacoran HTA
- Drosteakard
- Finoptin
- Flamon
- Geangin
- Hexasoptin
- Hexasoptin Retard
- Ikacor
- Ikapress
- Iproveratril
- Iproveratril hydrochloride
- Iproveratrilhydrochloride
- Iso-Card SR
- Isoptin
- Isoptin Retard
- Isoptin SR
- Isoptin, hydrochloride
- Isoptine
- Isoptino
- Izoptin hydrochloride
- Izoptinhydrochloride
- Lekoptin Retard
- Lu 20175
- Manidon
- Manidon Retard
- NSC 272366
- NSC 657799
- Novo-Veramil
- Quasar
- Ravamil SR
- Securon
- Univer
- Valeronitrile, 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-, hydrochloride
- Valeronitrile, 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-, monohydrochloride
- Vasolan
- Vasomil
- Vasopten
- Veracaps SR
- Veracim
- Veracor
- Verahexal
- Veraloc
- Veramex
- Veramil
- Verapamil HCl
- Verapin
- Verapress 240SR
- Veraptin
- Verdilac
- Verelan
- Verelan SR
- Verexamil
- Verogalid ER
- Verpal
- Vetrimil
- dl-Verapamil hydrochloride
- (+/-)-Verapamil hydrochloride
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