CAS 233277-99-1

4-Methyl-N-[(1S)-2-oxo-2-[[(1S)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propen-1-yl]amino]-1-(phenylmethyl)ethyl]-1-piperazinecarboxamide

Description:

4-Methyl-N-[(1S)-2-oxo-2-[[(1S)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propen-1-yl]amino]-1-(phenylmethyl)ethyl]-1-piperazinecarboxamide, with CAS number 233277-99-1, is a synthetic organic compound characterized by its complex molecular structure, which includes a piperazine ring, multiple aromatic groups, and a sulfonamide moiety. This compound is typically studied for its potential biological activity, particularly in the context of medicinal chemistry, where it may exhibit properties relevant to drug development. The presence of various functional groups suggests that it may engage in diverse interactions with biological targets, potentially influencing its pharmacological profile. Its stereochemistry, indicated by the (1S) configurations, suggests specific spatial arrangements that could be crucial for its activity and efficacy. As with many compounds of this nature, understanding its solubility, stability, and reactivity under different conditions is essential for evaluating its practical applications in therapeutic contexts. Further research would be necessary to elucidate its specific mechanisms of action and potential therapeutic uses.

Formula: C₃₂H₃₈N₄O₄S

InChI: InChI=1S/C32H38N4O4S/c1-35-20-22-36(23-21-35)32(38)34-30(25-27-13-7-3-8-14-27)31(37)33-28(18-17-26-11-5-2-6-12-26)19-24-41(39,40)29-15-9-4-10-16-29/h2-16,19,24,28,30H,17-18,20-23,25H2,1H3,(H,33,37)(H,34,38)/t28-,30-/m0/s1

InChI key: InChIKey=RHJLQMVZXQKJKB-JDXGNMNLSA-N

SMILES: [C@H](CC1=CC=CC=C1)(C(N[C@@H](CCC2=CC=CC=C2)C=CS(=O)(=O)C3=CC=CC=C3)=O)NC(=O)N4CCN(C)CC4

Synonyms:

• 1-Piperazinecarboxamide, 4-methyl-N-[(1S)-2-oxo-2-[[(1S)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propen-1-yl]amino]-1-(phenylmethyl)ethyl]-
• 1-Piperazinecarboxamide, 4-methyl-N-[(1S)-2-oxo-2-[[(1S)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propenyl]amino]-1-(phenylmethyl)ethyl]-
• 4-Methyl-N-[(1S)-2-oxo-2-[[(1S)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propen-1-yl]amino]-1-(phenylmethyl)ethyl]-1-piperazinecarboxamide
• Apc-3316
• Cra-3316
• K-11777
• K-777

K777

CAS: 233277-99-1

K777

Purity: ≥95%

Molecular weight: 574.73g/mol

Ref: 54-BUP01329

K777 [K11777]

CAS: 233277-99-1

Ref: 7W-GW4409

K777 Hydrochloride-d8

Controlled Product

CAS: 233277-99-1, 502960-92-1

Formula: C₃₂H₃₀D₈N₄O₄S·HCl

Color and Shape: Neat

Molecular weight: 619.24

Ref: TR-K165806

K-177

CAS: 233277-99-1

K-177 is a small molecule inhibitor that binds to the c-c chemokine receptor and prevents signaling. K-177 is a potent inhibitor of the c-c chemokine receptor, which has been implicated in the etiology of chronic diseases such as infectious diseases. It also inhibits other enzymes, such as hydrothiolation, but with minimal toxicity. The compound class includes molecules that are structurally related to K-177 and inhibit different targets. Some of these targets include kinases, protein tyrosine phosphatases, and RNA polymerase II. Kinetic data for K-177 have been obtained by titration calorimetry and kinetic modeling.

Formula: C₃₂H₃₈N₄O₄S

Purity: Min. 95%

Molecular weight: 574.73 g/mol

Ref: 3D-FK179029

K777

CAS: 233277-99-1

K777: Oral cysteine protease inhibitor, CYP3A4 blocker (IC50=60 nM), CCR4 antagonist, anti-Trypanosoma cruzi, antiviral, halts EBOV/SARS-CoV entry (IC50<1 nM).

Formula: C₃₂H₃₈N₄O₄S

Purity: 98.43% - 99.14%

Color and Shape: Solid

Molecular weight: 574.73

Ref: TM-T15641