CAS 23407-35-4

Methyl (αE,2S,3S,12bS)-3-ethyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)indolo[2,3-a]quinolizine-2-acetate

Description:

Methyl (αE,2S,3S,12bS)-3-ethyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)indolo[2,3-a]quinolizine-2-acetate, with CAS number 23407-35-4, is a complex organic compound characterized by its unique indoloquinolizine structure. This substance features multiple stereocenters, contributing to its potential chiral properties, which may influence its biological activity and interactions. The presence of an acetate group suggests it may participate in esterification reactions, while the methoxymethylene moiety indicates potential reactivity in nucleophilic addition or substitution reactions. Its octahydro framework implies a saturated cyclic structure, which can affect its solubility and stability. The compound may exhibit pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. However, detailed studies on its specific physical and chemical properties, such as solubility, melting point, and reactivity, would be necessary to fully understand its behavior in various environments. As with many complex organic compounds, safety and handling precautions should be observed due to potential biological activity.

Formula: C₂₂H₂₈N₂O₃

InChI: InChI=1S/C22H28N2O3/c1-4-14-12-24-10-9-16-15-7-5-6-8-19(15)23-21(16)20(24)11-17(14)18(13-26-2)22(25)27-3/h5-8,13-14,17,20,23H,4,9-12H2,1-3H3/b18-13+/t14-,17+,20+/m1/s1

InChI key: InChIKey=NMLUOJBSAYAYEM-QALMDFCDSA-N

SMILES: C(\C(OC)=O)(=C/OC)/[C@H]1C[C@]2(C3=C(C=4C(N3)=CC=CC4)CCN2C[C@H]1CC)[H]

Synonyms:

• 17,18-Seco-20α-yohimban-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (E)-
• Corynan-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (16E,20β)-
• Corynantheidine
• Epidihydrocorynantheine
• Indolo(2,3-a)quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,12,12b-octahydro-alpha-(methoxymethylene)-, methyl ester, (alphaE,2S,3S,12bS)-
• Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, (αE,2S,3S,12bS)-
• Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, [2S-[2α(E),3α,12bβ]]-
• Methyl (αE,2S,3S,12bS)-3-ethyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)indolo[2,3-a]quinolizine-2-acetate

Corynantheidine

CAS: 23407-35-4

Corynantheidine ((-)-Corynantheidine) is a partial agonist of the mu opioid receptor (MOR) and demonstrates MOR-dependent analgesic effects in mice.

Formula: C₂₂H₂₈N₂O₃

Color and Shape: Solid

Molecular weight: 368.47

Ref: TM-T203189

Corynantheidine

CAS: 23407-35-4

Formula: C₂₂H₂₈N₂O₃

Molecular weight: 368.48

Ref: 4Z-C-501001

(-)-Corynantheidine

Controlled Product

CAS: 23407-35-4

Formula: C₂₂H₂₈N₂O₃

Color and Shape: Neat

Molecular weight: 368.469

Ref: TR-C685605

(-)-Corynantheidine

CAS: 23407-35-4

(-)-Corynantheidine is a tylosin analog that has been found to exhibit potent anticancer activity. It is a kinase inhibitor that can induce apoptosis in various types of cancer cells, including human tumor cells. (-)-Corynantheidine has been shown to inhibit the activity of several kinases, including those involved in cell growth and division. This compound also exhibits anti-inflammatory properties and can reduce the production of pro-inflammatory cytokines. Additionally, (-)-Corynantheidine has menthol-like properties and can be detected in urine samples. Its potential as an anticancer agent makes it a promising candidate for further research and development of cancer treatments.

Formula: C₂₂H₂₈N₂O₃

Purity: Min. 95%

Molecular weight: 368.5 g/mol

Ref: 3D-YAA40735