CAS 2341-22-2
:5-Fluorocytidine
Description:
5-Fluorocytidine is a nucleoside analog of cytidine, characterized by the substitution of a fluorine atom at the 5-position of the pyrimidine ring. This modification alters its biological properties, making it of interest in cancer research and antiviral therapies. The molecular formula of 5-Fluorocytidine is C9H11FN2O5, and it has a molecular weight that reflects its structure. As a nucleoside, it consists of a pyrimidine base (5-fluorouracil) linked to a ribose sugar. 5-Fluorocytidine is known to interfere with RNA synthesis and can inhibit the growth of certain cancer cells by disrupting normal nucleic acid metabolism. It is often studied for its potential use in combination therapies, particularly in the treatment of solid tumors and viral infections. The compound is typically administered in a pharmaceutical context, and its efficacy and safety profiles are subjects of ongoing research. As with many nucleoside analogs, its mechanism of action involves incorporation into RNA, leading to faulty protein synthesis and ultimately cell death.
Formula:C9H12FN3O5
InChI:InChI=1S/C9H12FN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1
InChI key:InChIKey=STRZQWQNZQMHQR-UAKXSSHOSA-N
SMILES:O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C(F)=C2
Synonyms:- 4-amino-5-fluoro-1-(beta-L-ribofuranosyl)pyrimidin-2(1H)-one
- Amino(2-Fluorophenyl)Acetic Acid
- Cytidine, 5-fluoro-
- 5-Fluorocytidine
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Found 10 products.
5-Fluorocytidine
CAS:Formula:C9H12FN3O5Purity:>97.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:261.215-Fluorocytidine
CAS:<p>5-Fluorocytidine with antiviral activity</p>Formula:C9H12FN3O5Purity:99.23%Color and Shape:White PowderMolecular weight:261.215-Fluorocytidine
CAS:<p>5-Fluorocytidine</p>Formula:C9H12FN3O5Purity:95%Color and Shape: white solidMolecular weight:261.21g/mol5-Fluoro Cytidine
CAS:Controlled Product<p>Applications 5-Fluoropyrimidine nucleotides as probes of RNA structure using 19F-NMR spectroscopy.<br>References Metzler, W., et al.: J. Magn. Reson., 76, 534 (1988), de Dios, A., et al.: Science, 260, 1491 (1993), Kulinski, T., et al.: J. Biol. Chem., 278, 38892 (2003),<br></p>Formula:C9H12FN3O5Color and Shape:NeatMolecular weight:261.215-Fluorocytidine
CAS:<p>5-Fluorocytidine (5FC) is an antiviral drug that inhibits the synthesis of DNA. 5FC is a prodrug that is converted to cytosine in vivo, and then incorporated into viral DNA by polymerase chain reactions. The incorporation of 5FC into viral DNA prevents replication and transcription, which can lead to the death of cells infected with HIV. In addition, 5FC has been shown to be effective in treating chronic viral hepatitis and bowel diseases such as Crohn's disease. It also has potential use as a drug target for cancer treatments.<br>5FC has been shown to inhibit transcription activators in murine hepatoma cells and inhibit the growth of tumors in transfection experiments using human colon cancer cells. This antiviral agent has also been shown to have antimicrobial activity against Gram-positive bacteria, including Clostridium difficile, Staphylococcus aureus, Streptococcus pyogenes and Enterococcus faec</p>Formula:C9H12FN3O5Purity:Min. 99 Area-%Color and Shape:White PowderMolecular weight:261.21 g/mol
