CAS 2342576-75-2

5-Isoxazolecarboxamide, 3-[(4′-chloro[1,1′-biphenyl]-4-yl)methoxy]-N-hydroxy-

Description:

5-Isoxazolecarboxamide, 3-[(4′-chloro[1,1′-biphenyl]-4-yl)methoxy]-N-hydroxy- is a chemical compound characterized by its isoxazole ring, which contributes to its heterocyclic structure. The presence of a carboxamide functional group indicates potential for hydrogen bonding, influencing its solubility and reactivity. The compound features a chloro-substituted biphenyl moiety, which may enhance its lipophilicity and biological activity. The methoxy group attached to the biphenyl structure can also affect the compound's electronic properties and steric hindrance. As a result, this compound may exhibit interesting pharmacological properties, making it a candidate for further research in medicinal chemistry. Its specific interactions with biological targets would depend on the overall three-dimensional conformation and electronic distribution, which are influenced by the substituents on the isoxazole and biphenyl rings. The CAS number 2342576-75-2 uniquely identifies this compound, facilitating its study and application in various scientific fields, including drug development and materials science.

Formula: C₁₇H₁₃ClN₂O₄

Synonyms:

• 5-Isoxazolecarboxamide, 3-[(4′-chloro[1,1′-biphenyl]-4-yl)methoxy]-N-hydroxy-

ASM-IN-3

CAS: 2342576-75-2

ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.

Formula: C₁₇H₁₃ClN₂O₄

Color and Shape: Solid

Molecular weight: 344.75

Ref: TM-T203687