CAS 23451-01-6

Physcion 8-O-β-D-glucopyranoside

Description:

Physcion 8-O-β-D-glucopyranoside, with the CAS number 23451-01-6, is a naturally occurring compound belonging to the anthraquinone class of compounds. It is characterized by its glycosidic structure, which consists of a physcion moiety linked to a β-D-glucopyranoside unit. This compound is typically derived from various plant sources, particularly those in the Rhamnaceae family. Physcion 8-O-β-D-glucopyranoside exhibits several biological activities, including antioxidant, anti-inflammatory, and potential anticancer properties, making it of interest in pharmacological research. Its solubility is influenced by the glycoside nature, which generally enhances its water solubility compared to its aglycone counterpart. The compound's stability and reactivity can vary based on environmental conditions such as pH and temperature. Additionally, it may undergo enzymatic hydrolysis in biological systems, releasing the aglycone and glucose, which can further contribute to its biological effects. Overall, Physcion 8-O-β-D-glucopyranoside represents a significant compound in the study of natural products and their therapeutic potentials.

Formula: C₂₂H₂₂O₁₀

InChI: InChI=1S/C22H22O10/c1-8-3-10-15(12(24)4-8)19(27)16-11(17(10)25)5-9(30-2)6-13(16)31-22-21(29)20(28)18(26)14(7-23)32-22/h3-6,14,18,20-24,26,28-29H,7H2,1-2H3/t14-,18-,20+,21-,22-/m1/s1

InChI key: InChIKey=POMKXWCJRHNLRP-DQMLXFRHSA-N

SMILES: O(C1=C2C(C(=O)C=3C(C2=O)=C(O)C=C(C)C3)=CC(OC)=C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Synonyms:

• Physcion 8-O-β-D-glucoside
• Physcion 8-β-D-glucopyranoside
• Glucopyranoside, 8-hydroxy-3-methoxy-6-methyl-1-anthraquinonyl, β-D-
• 9,10-Anthracenedione, 1-(β-D-glucopyranosyloxy)-8-hydroxy-3-methoxy-6-methyl-
• 1-(β-D-Glucopyranosyloxy)-8-hydroxy-3-methoxy-6-methyl-9,10-anthracenedione

Physcion-8-O-β-D-glucoside

CAS: 23451-01-6

Formula: C₂₂H₂₂O₁₀

Purity: 99%

Color and Shape: Solid

Molecular weight: 446.4041

Ref: IN-DA00C2EZ

Physcion 8-O-β-D-glucopyranoside

CAS: 23451-01-6

Physcion 8-O-β-D-glucopyranoside

Purity: ≥98%

Molecular weight: 446.4g/mol

Ref: 54-BUP00867

Physcion 8-glucoside

CAS: 23451-01-6

Formula: C₂₂H₂₂O₁₀

Purity: 95%~99%

Molecular weight: 446.408

Ref: BP-BP4506

Physcion 8-O-β-D-glucopyranoside

CAS: 23451-01-6

Physcion 8-O-β-D-glucopyranoside (Physcion 8-O-beta-D-monoglucoside) has anti-inflammatory and anti-cancer activities.

Formula: C₂₂H₂₂O₁₀

Purity: 99.8%

Color and Shape: Solid

Molecular weight: 446.4

Ref: TM-TN2064

Physcion 8-β-D-glucoside

CAS: 23451-01-6

Applications Physcion 8-β-D-glucoside has been studied in research relating to the treatment of the glomerulonephritis. It is the glucoside of Physcion (P398000) which is a natural anthraquinone derivative, on the infection process of Blumeria graminis on wheat. Physcion is one of the important active ingredients of ethanol extract from the roots of Chinese rhubarb (Rheum officinale) for controlling powdery mildew.
References Kuo, Y.C. et al.: Life. Sci., 68, 1271 (2001); Thiericke, R., et al.: Nat. Prod. Rep.,10, 265 (1993); Lin, C., et al.: J. Nat. Prod., 58, 1934 (1995); Julia, S., et al.: J. Biotechnol., 124, 690 (2006); Wang, W., et al.: J. Antibiot., 60, 603 (2007);

Formula: C₂₂H₂₂O₁₀

Color and Shape: Yellowish Solid

Molecular weight: 446.40

Ref: TR-P398100

Physcion 8-β-D-glucoside

CAS: 23451-01-6

Physcion 8-β-D-glucoside is a natural anthraquinone glycoside, which is primarily derived from the plant Emodin. This compound is known for its role in plant defense mechanisms with a mode of action that includes the inhibition of fungal growth and the disruption of fungal cell division. By affecting critical biological processes in fungi, it impairs their ability to proliferate, serving as an effective antifungal agent.

Formula: C₂₂H₂₂O₁₀

Purity: Min. 95%

Molecular weight: 446.4 g/mol

Ref: 3D-YAA45101