CAS 23458-02-8

(+)-Decursinol

Description:

(+)-Decursinol is a naturally occurring compound classified as a phenolic glycoside, primarily derived from the plant species Angelica decursiva. It is characterized by its chiral nature, with the "(+)" designation indicating its specific optical activity. The molecular structure of (+)-Decursinol features a fused ring system, which contributes to its biological activity. This compound has garnered interest in the field of medicinal chemistry due to its potential pharmacological properties, including anti-inflammatory, antioxidant, and anticancer activities. Its solubility profile typically indicates moderate solubility in organic solvents, while its stability can be influenced by environmental factors such as pH and temperature. Research into (+)-Decursinol continues to explore its mechanisms of action and potential therapeutic applications, making it a subject of interest in both natural product chemistry and drug development. As with many natural compounds, the extraction and purification processes are crucial for obtaining (+)-Decursinol in a form suitable for further study and application.

Formula: C₁₄H₁₄O₄

InChI: InChI=1/C14H14O4/c1-14(2)12(15)6-9-5-8-3-4-13(16)17-10(8)7-11(9)18-14/h3-5,7,12,15H,6H2,1-2H3/t12-/m0/s1

InChI key: InChIKey=BGXFQDFSVDZUIW-LBPRGKRZSA-N

SMILES: O[C@H]1CC=2C(=CC3=C(C2)C=CC(=O)O3)OC1(C)C

Synonyms:

• (+)-Decursinol
• (3S)-3-Hydroxy-2,2-dimethyl-3,4-dihydropyrano[3,2-g]chromen-8-one
• (7S)-7,8-Dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b′]dipyran-2-one
• (S)-7-Hydroxy-8,8-dimethyl-7,8-dihydropyrano(3,2-g)chromen-2(6H)-one
• 2H,6H-Benzo[1,2-b:5,4-b′]dipyran-2-one, 7,8-dihydro-7-hydroxy-8,8-dimethyl-, (7S)-
• 2H,6H-Benzo[1,2-b:5,4-b′]dipyran-2-one, 7,8-dihydro-7-hydroxy-8,8-dimethyl-, (S)-
• Smirinol
• Smyrinol
• (7S)-7α-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one
• ecursinol
• (S)-7,8-Dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one

Decursinol

CAS: 23458-02-8

Formula: C₁₄H₁₄O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 246.2586

Ref: IN-DA00BJKV

Decursinol

CAS: 23458-02-8

Decursinol

Purity: ≥98%

Molecular weight: 246.26g/mol

Ref: 54-BUP08964

Decursinol

CAS: 23458-02-8

Formula: C₁₄H₁₄O₄

Molecular weight: 246.26

Ref: 7W-GY9050

Decursinol

CAS: 23458-02-8

Decursinol may be a beneficial antimetastatic agent, targeting MMPs and its upstream signaling molecules; it inhibits the proliferation and invasion of CT-26 colon carcinoma cells, might via downregulated ERK and JNK phosphorylation. Aspirin-decursinol has neuroprotective effects, may be closely related to the attenuation of ischemia-induced gliosis and maintenance of antioxidants.

Formula: C₁₄H₁₄O₄

Purity: 95%~99%

Molecular weight: 246.262

Ref: BP-BPF2775

Decursinol

CAS: 23458-02-8

Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity.

Formula: C₁₄H₁₄O₄

Purity: 99.19% - 99.77%

Color and Shape: Solid

Molecular weight: 246.26

Ref: TM-T8169

Decursinol

CAS: 23458-02-8

Lactone

Formula: C₁₄H₁₄O₄

Purity: ≥ 90.0 % (HPLC)

Molecular weight: 246.26

Ref: 5G-84208

Decursinol

CAS: 23458-02-8

Decursinol is a coumarin derivative, which is sourced from the roots of the plant Angelica gigas, commonly found in East Asia. The compound is recognized for its biochemical properties, specifically as a secondary metabolite in the umbelliferous family. Its mode of action involves the inhibition of key inflammatory pathways, notably through the suppression of pro-inflammatory cytokines and enzymes such as COX-2 and NF-κB. This molecular interaction effectively reduces inflammatory responses at the cellular level.

Formula: C₁₄H₁₄O₄

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 246.26 g/mol

Ref: 3D-FD158147