CAS 2347368-51-6

Cyclopropanecarboxylic acid, 2-[4-[7-cyclopropyl-5-[[(1R)-3,4-dihydro-1-methyl-2(1H)-isoquinolinyl]carbonyl]pyrazolo[1,5-a]pyrimidin-2-yl]-3-fluorophenyl]-, (1S,2S)-

Description:

Cyclopropanecarboxylic acid, 2-[4-[7-cyclopropyl-5-[[(1R)-3,4-dihydro-1-methyl-2(1H)-isoquinolinyl]carbonyl]pyrazolo[1,5-a]pyrimidin-2-yl]-3-fluorophenyl]-, (1S,2S)- is a complex organic compound characterized by its unique structural features, including a cyclopropane ring and multiple functional groups. This compound exhibits properties typical of carboxylic acids, such as the ability to form hydrogen bonds, which can influence its solubility and reactivity. The presence of the cyclopropyl group may impart strain, affecting the compound's stability and reactivity. Additionally, the incorporation of a pyrazolo[1,5-a]pyrimidine moiety suggests potential biological activity, as many derivatives of this class are known for their pharmacological properties. The specific stereochemistry indicated by (1S,2S)- suggests that the compound may exhibit chirality, which can significantly influence its interaction with biological targets. Overall, this compound's intricate structure and functional groups make it a subject of interest in medicinal chemistry and drug development.

Formula: C₃₀H₂₇FN₄O₃

Synonyms:

• Cyclopropanecarboxylic acid, 2-[4-[7-cyclopropyl-5-[[(1R)-3,4-dihydro-1-methyl-2(1H)-isoquinolinyl]carbonyl]pyrazolo[1,5-a]pyrimidin-2-yl]-3-fluorophenyl]-, (1S,2S)-

JNJ-7184

CAS: 2347368-51-6

JNJ-7184 is a non-nucleoside inhibitor of the RSV-Large (L) polymerase, with pEC50 and pCC50 values of 7.86 and 4.29, respectively, in Hela cells. It inhibits the initiation or early elongation phases, thereby preventing RSV replication and transcription.

Formula: C₃₀H₂₇FN₄O₃

Color and Shape: Solid

Molecular weight: 510.56

Ref: TM-T88791