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CAS 23495-06-9

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Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, labeled with tritium, (11β,16α)-

Description:
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, labeled with tritium, is a synthetic steroid compound that exhibits characteristics typical of glucocorticoids. This compound features a steroid backbone with multiple hydroxyl groups, which contribute to its biological activity, particularly in modulating inflammation and immune responses. The presence of a fluorine atom enhances its potency and metabolic stability. The tritium labeling indicates that it is used in research to trace metabolic pathways or receptor interactions in biological systems. As a glucocorticoid, it likely binds to the glucocorticoid receptor, influencing gene expression and cellular responses. Its structural modifications, such as the 9-fluoro and 16-methyl groups, can affect its pharmacokinetics and pharmacodynamics, making it a valuable compound in both therapeutic and research contexts. Overall, this compound exemplifies the complexity and utility of modified steroid hormones in medicinal chemistry.
Formula:C22H29FO5
Synonyms:
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, labeled with tritium
  • 3H-Dexamethasone
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, labeled with tritium, (11β,16α)-
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