CAS 2351218-88-5

7-(5-((4-(4-(N,N-Dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetyl)piperazin-1-yl)ethyl)-3-(3-

CAS: 2351218-88-5

7-(5-((4-(4-(N,N-Dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetyl)piperazin-1-yl)ethyl)-3-(3-

Purity: 98%

Molecular weight: 1163.32g/mol

Ref: 54-OR1073800

dMCL1-2

CAS: 2351218-88-5

dMCL1-2 is a PROTAC-based MCL1 degrader, binding at 30 nM, and induces apoptosis in leukemia.

Formula: C₆₁H₆₆N₁₀O₁₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 1163.3

Ref: TM-T13657

dMCL1-2

CAS: 2351218-88-5

N-Acetyl-3,4-dihydro-2-(2,6-dioxo-3-piperidinopyrimidin-1(2H)-yl)isoindoline-4-carboxylic acid is a potent immunostimulatory and anticancer drug. It is a homologous compound that induces activation of the immune system through h3 acetylation. NAA [N-Acetyl-3,4-dihydro-2-(2,6-dioxo-3piperidinopyrimidin 1(2H)-yl)isoindoline 4 carboxylic acid] has been shown to have regulatory effects on a number of other cell types. In vitro studies with MDA MB231 breast cancer cells showed that NAA induced apoptosis in these cells through the inhibition of histone h3 acetylation and increased expression of effector proteins such as all trans ret

Formula: C₆₁H₆₆N₁₀O₁₂S

Purity: Min. 95%

Molecular weight: 1,163.3 g/mol

Ref: 3D-BUD21888