Gly-Gly-Gly-PEG3-TCO is a synthetic compound that combines a peptide sequence with a polyethylene glycol (PEG) moiety and a trans-cyclooctene (TCO) functional group. The presence of the Gly-Gly-Gly peptide sequence suggests that it may be involved in bioconjugation or drug delivery applications, as glycine is a simple amino acid that can facilitate interactions with biological systems. The PEG component enhances solubility, biocompatibility, and reduces immunogenicity, making it suitable for use in pharmaceuticals and biotechnology. The TCO group is a reactive moiety that can participate in bioorthogonal reactions, particularly with tetrazines, allowing for selective labeling or conjugation in complex biological environments. Overall, Gly-Gly-Gly-PEG3-TCO is characterized by its multifunctionality, combining the properties of peptides, polymers, and reactive groups, which makes it a valuable tool in chemical biology and therapeutic development. Its specific applications may vary based on the context of use, including targeted drug delivery, imaging, or the development of novel biomaterials.

Gly-Gly-Gly-PEG3-TCO is a cleavable PEG linker used in the synthesis of antibody-drug conjugates.

Gly-Gly-Gly-PEG3-TCO

2353409-81-9: Gly-Gly-Gly-PEG3-TCO is a synthetic compound that combines a peptide sequence with a polyethylene glycol (PEG) moiety and a trans-cyclooctene (TCO) functional group. The presence of the Gly-Gly-Gly peptide sequence suggests that it may be involved in bioconjugation or drug delivery applications, as glycine is a simple amino acid that can facilitate interactions with biological systems. The PEG component enhances solubility, biocompatibility, and reduces immunogenicity, making it suitable for use in pharmaceuticals and biotechnology. The TCO group is a reactive moiety that can participate in bioorthogonal reactions, particularly with tetrazines, allowing for selective labeling or conjugation in complex biological environments. Overall, Gly-Gly-Gly-PEG3-TCO is characterized by its multifunctionality, combining the properties of peptides, polymers, and reactive groups, which makes it a valuable tool in chemical biology and therapeutic development. Its specific applications may vary based on the context of use, including targeted drug delivery, imaging, or the development of novel biomaterials.

<p>Gly-Gly-Gly-PEG3-TCO is a cleavable three-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].</p>

CAS 2353409-81-9

Gly-Gly-Gly-PEG3-TCO

Gly-Gly-Gly-PEG3-TCO

Ref: 54-OR1037100

Gly-Gly-Gly-PEG3-TCO

Ref: TM-T17986