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CAS 23583-48-4

:

8-Bromo-cAMP

Description:
8-Bromo-cAMP, with the CAS number 23583-48-4, is a synthetic derivative of cyclic adenosine monophosphate (cAMP), a crucial second messenger in various biological processes. This compound is characterized by the presence of a bromine atom at the 8-position of the adenine ring, which enhances its stability and alters its biological activity compared to natural cAMP. 8-Bromo-cAMP is often used in biochemical research to study signal transduction pathways, particularly those involving protein kinase A (PKA), as it can mimic the effects of cAMP while being resistant to degradation by phosphodiesterases. The compound is typically soluble in water and organic solvents, making it versatile for laboratory applications. Its ability to activate PKA and influence cellular responses makes it a valuable tool in pharmacology and cell biology. However, like many chemical substances, it should be handled with care, following appropriate safety protocols due to its potential biological effects.
Formula:C10H11BrN5O6P
InChI:InChI=1/C10H11BrN5O6P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14)/t3-,5-,6-,9-/m1/s1
InChI key:InChIKey=DVKQVRZMKBDMDH-UUOKFMHZSA-N
SMILES:BrC=1N(C=2C(N1)=C(N)N=CN2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(=O)(O)O4)[H])[H]
Synonyms:
  • (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide
  • 23583-48-4
  • 3',5'-(Hidrogenofosfato) Ciclico De 8-Bromoadenosina
  • 3',5'-(Hydrogenophosphate) Cyclique De 8-Bromoadenosine
  • 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.
  • 6-(6-amino-8-bromo-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide
  • 8-Bromadenosin-cyclisch-3',5'-(hydrogenphosphat)
  • 8-Bromo-cAMP
  • 8-Bromo-cyclic 3',5'-AMP
  • 8-Bromo-cyclic 3′,5′-AMP
  • See more synonyms
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Found 7 products.
  • 8-Bromoadenosine-3',5'-cyclic monophosphate
    Alfa Aesar By Thermo Fisher Scientific
    + Info

    8-Bromoadenosine-3',5'-cyclic monophosphate

    CAS:
    <p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>
    Formula:C10H11BrN5O6P
    Molecular weight:408.11

    Ref: 02-J64469

    50mg
    To inquire
    100mg
    306.00€
    250mg
    609.00€
  • 8-Bromoadenosine cyclic 3',5'-monophosphate
    Indagoo
    + Info

    8-Bromoadenosine cyclic 3',5'-monophosphate

    CAS:
    Formula:C10H11BrN5O6P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:408.1020

    Ref: IN-DA002NRS

    1g
    To inquire
    5mg
    50.00€
    25mg
    114.00€
    50mg
    182.00€
    100mg
    221.00€
    250mg
    497.00€
  • 8-Bromoadenosine 3'',5''-cyclic monophosphate
    Glentham
    + Info

    8-Bromoadenosine 3'',5''-cyclic monophosphate

    CAS:
    Formula:C10H11BrN5O6P
    Molecular weight:408.11

    Ref: 7W-GN1084

    ne
    To inquire
  • CymitQuimica logo
    Apollo Scientific
    + Info

    8-Bromo-cAMP

    CAS:
    8-Bromo-cAMP
    Purity:≥95%
    Molecular weight:408.1g/mol

    Ref: 54-OR1005158

    1g
    1,184.00€
  • 8-Bromo-cAMP
    Targetmol
    + Info

    8-Bromo-cAMP

    CAS:
    <p>8-Bromo-cAMP is a cell-permeable cAMP analogue and activator of CAMP-dependent protein kinase A that induces cell death and reduces proliferation.</p>
    Formula:C10H11BrN5O6P
    Purity:97.30%
    Color and Shape:Solid
    Molecular weight:408.1

    Ref: TM-T35424

  • 8-Bromoadenosine 3',5'-cyclic monophosphate
    Biosynth
    + Info

    8-Bromoadenosine 3',5'-cyclic monophosphate

    CAS:
    <p>8-Bromoadenosine 3',5'-cyclic monophosphate (8-Br-cAMP) is a cyclic nucleotide that is involved in the regulation of energy metabolism. It is a pharmacological agent that regulates the intracellular levels of cAMP and plays an important role in regulating cell proliferation, differentiation, and survival. 8-Br-cAMP binds to specific protein kinases and alters their activity. It also inhibits the enzymatic activity of DNA polymerase II. 8-Br-cAMP has been shown to inhibit tumor growth in mice with bone cancer. The mechanism by which this drug exerts its antitumor effect appears to be related to increased expression of basic proteins and decreased expression of phosphatase 2A, leading to increased activation of protein kinase A. 8-Br-cAMP also causes cellular accumulation of Ca2+ ions by stimulating an increase in the activity of phospholipase C, which hydrolyzes phosphat</p>
    Formula:C10H11BrN5O6P
    Purity:Min. 98 Area-%
    Color and Shape:Beige Powder
    Molecular weight:408.11 g/mol

    Ref: 3D-NB07972

    1g
    1,611.00€
    2g
    2,951.00€
    100mg
    475.00€
    250mg
    708.00€
    500mg
    1,003.00€
  • 8-Bromo-cAMP
    Fluorochem
    + Info

    8-Bromo-cAMP

    CAS:
    Purity:98%
    Molecular weight:406.96

    Ref: 10-F554595

    1g
    882.00€