CAS 23593-75-1

Clotrimazole

Description:

Clotrimazole is an antifungal medication belonging to the imidazole class, primarily used to treat various fungal infections, including those caused by dermatophytes and yeast. It functions by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting their integrity and leading to cell death. Clotrimazole is typically administered topically in creams, lotions, or solutions for skin infections, as well as in lozenge form for oral thrush. The substance is characterized by its white to off-white crystalline powder appearance and is sparingly soluble in water but more soluble in organic solvents like ethanol and acetone. Its molecular formula is C22H17ClN2, and it has a molecular weight of approximately 344.84 g/mol. Clotrimazole is generally well-tolerated, with side effects being rare and usually mild, such as local irritation or allergic reactions. It is important to follow appropriate guidelines for use to ensure efficacy and minimize resistance development.

Formula: C₂₂H₁₇ClN₂

InChI: InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H

InChI key: InChIKey=VNFPBHJOKIVQEB-UHFFFAOYSA-N

SMILES: C(C1=C(Cl)C=CC=C1)(N2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4

Synonyms:

• (2-Chlorophenyl)diphenyl-1-imidazolylmethane
• 1-(o-Chlorophenyldiphenylmethyl)imidazole
• 1-(o-Chlorotrityl)imidazole
• 1H-Imidazole, 1-[(2-chlorophenyl)diphenylmethyl]-
• 1[(2-chlorophenyl)diphenylmethyl]-1H-imidazole
• Agisten
• Bay 5097
• Bay 5907
• Bay-B 5097
• Canesten
• Canifug
• Clotrimazol
• Clotrimazole
• Clotrimazole ZnSO4 complex
• Desamix F
• Diphenyl(2-chlorophenyl)(1-imidazolyl)methane
• Empecid
• Femcare
• Gyne-Lotrimin
• Gyne-Lotrimin 7
• Imidazole, 1-(o-chloro-α,α-diphenylbenzyl)-
• Locasten
• Lotrimin
• Lotrimin AF Cream
• Lotrimin AF Solution
• Lotrimin Jock-Itch Cream
• Lotrimin Jock-Itch Lotion
• Monobaycuten
• Mycelex
• Mycelex 7
• Mycelex G
• Mycelex OTC
• Mycelex Troche
• Mycofug
• Mycosporin
• Nsc 257473
• Pedisafe
• Plimycol
• Rimazole
• Tibatin
• Trimysten

Clotrimazole

CAS: 23593-75-1

Formula: C₂₂H₁₇ClN₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 344.84

Ref: 3B-C2867

Clotrimazole

CAS: 23593-75-1

Specific inhibitor of calcium-activated potassium channels

Formula: C₂₂H₁₇ClN₂

Molecular weight: 344.84

Ref: 02-J63895

CLOTRIMAZOLE CRS

CAS: 23593-75-1

CLOTRIMAZOLE CRS

Formula: C₂₂H₁₇ClN₂

Color and Shape: Crystalline Powder. White. Yellow. Powder.

Molecular weight: 344.8368

Ref: 41-C2430000

CLOTRIMAZOLE FOR PEAK IDENTIFICATION CRS

CAS: 23593-75-1

CLOTRIMAZOLE FOR PEAK IDENTIFICATION CRS

Formula: C₂₂H₁₇ClN₂

Molecular weight: 344.8368

Ref: 41-Y0000849

Clotrimazole

CAS: 23593-75-1

Clotrimazole

Formula: C₂₂H₁₇ClN₂

Purity: 99.8%

Color and Shape: Off White Solid

Molecular weight: 344.10803

Ref: 47-379

Clotrimazole

CAS: 23593-75-1

Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoi

Formula: C₂₂H₁₇ClN₂

Color and Shape: White Light Yellow Powder

Molecular weight: 344.10803

Ref: 45-1141002

Clotrimazole

CAS: 23593-75-1

Clotrimazole (FB 5097), an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol.

Formula: C₂₂H₁₇ClN₂

Purity: 99.89%

Color and Shape: Crystals Solid

Molecular weight: 344.84

Ref: TM-T0506

Clotrimazole

CAS: 23593-75-1

Clotrimazole

Purity: ≥95%

Molecular weight: 344.843g/mol

Ref: 54-OR98300

Clotrimazole

CAS: 23593-75-1

Formula: C₂₂H₁₇ClN₂

Purity: 98.0 - 100.5 % (dried basis)

Color and Shape: White or pale yellow powder

Molecular weight: 344.84

Ref: 7W-GA8137

Clotrimazole

CAS: 23593-75-1

Clotrimazole

Purity: ≥98%

Molecular weight: 344.84g/mol

Ref: 54-BUP18377

Clotrimazole 100 µg/mL in Acetonitrile

Controlled Product

CAS: 23593-75-1

Formula: C₂₂H₁₇ClN₂

Color and Shape: Single Solution

Molecular weight: 344.84

Ref: 04-A11692000AL-100

Clotrimazole

Controlled Product

CAS: 23593-75-1

Formula: C₂₂H₁₇ClN₂

Color and Shape: Neat

Molecular weight: 344.84

Ref: 04-C11692000

Clotrimazole

CAS: 23593-75-1

Color and Shape: Neat

Ref: 86-MM0015.00

Clotrimazole

CAS: 23593-75-1

Formula: C₂₂H₁₇ClN₂

Molecular weight: 344.85

Ref: 4Z-C-262

Clotrimazole

CAS: 23593-75-1

Applications Clotrimazole is an antifungal agent.
References Podust, L., et al.: J. Biol. Chem., 284, 25211 (2009), Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009), Marciniec, B., et al.: J. Pharm. Biomed. Anal., 50, 675 (2009), McGinnity, D., et al.: Drug Metab. Disposition, 37, 1259 (2009),

Formula: C₂₂H₁₇ClN₂

Color and Shape: Neat

Molecular weight: 344.84

Ref: TR-C587400

Clotrimazole

CAS: 23593-75-1

Clotrimazole is an azole antifungal medication with action on fungal cell membrane disruption and is used for treating fungal infections like athlete's foot, ringworm, and vaginal yeast infections.

Formula: C₂₂H₁₇ClN₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 344.84 g/mol

Ref: 3D-FC20523

Clotrimazole

CAS: 23593-75-1

Formula: C₂₂H₁₇ClN₂

Purity: 95+%

Color and Shape: Crystalline Powder,Powder

Molecular weight: 344.84

Ref: 10-F492467

1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole

CAS: 23593-75-1

Formula: C₂₂H₁₇ClN₂

Color and Shape: Solid

Molecular weight: 344.8368

Ref: IN-DA00393K

Clotrimazole

CAS: 23593-75-1

Color and Shape: Neat

Ref: 61-FOR0015.00