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CAS 23593-75-1

:

Clotrimazole

Description:
Clotrimazole is an antifungal medication belonging to the imidazole class, primarily used to treat various fungal infections, including those caused by dermatophytes and yeast. It functions by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting their integrity and leading to cell death. Clotrimazole is typically administered topically in creams, lotions, or solutions for skin infections, as well as in lozenge form for oral thrush. The substance is characterized by its white to off-white crystalline powder appearance and is sparingly soluble in water but more soluble in organic solvents like ethanol and acetone. Its molecular formula is C22H17ClN2, and it has a molecular weight of approximately 344.84 g/mol. Clotrimazole is generally well-tolerated, with side effects being rare and usually mild, such as local irritation or allergic reactions. It is important to follow appropriate guidelines for use to ensure efficacy and minimize resistance development.
Formula:C22H17ClN2
InChI:InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
InChI key:InChIKey=VNFPBHJOKIVQEB-UHFFFAOYSA-N
SMILES:C(C1=C(Cl)C=CC=C1)(N2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4
Synonyms:
  • (2-Chlorophenyl)diphenyl-1-imidazolylmethane
  • 1-(o-Chlorophenyldiphenylmethyl)imidazole
  • 1-(o-Chlorotrityl)imidazole
  • 1H-Imidazole, 1-[(2-chlorophenyl)diphenylmethyl]-
  • 1[(2-chlorophenyl)diphenylmethyl]-1H-imidazole
  • Agisten
  • Bay 5097
  • Bay 5907
  • Bay-B 5097
  • Canesten
  • See more synonyms
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