CAS 2361146-30-5

GSK840

Controlled Product

CAS: 2361146-30-5

GSK840 is a potent inhibitor of kinase activity, which plays an important role in regulating cell growth and apoptosis. It has been shown to induce apoptosis in human cancer cells and inhibit the growth of tumors in mice. GSK840 is an analog of nintedanib, another kinase inhibitor that has been approved for the treatment of certain cancers. GSK840 inhibits a wide range of kinases, including those involved in cancer cell proliferation and survival. It can be detected in urine after administration and has high protein binding capacity. GSK840 shows promising anticancer activity and may have potential as a therapeutic agent for various types of cancer. Its effectiveness against Chinese hamster ovary cells also suggests its potential as a tool compound for research purposes.

Formula: C₂₁H₂₃N₃O₃

Purity: Min. 95%

Molecular weight: 365.4 g/mol

Ref: 3D-LUD14630

GSK840

CAS: 2361146-30-5

GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase

Formula: C₂₁H₂₃N₃O₃

Purity: 99.7%

Color and Shape: Solid

Molecular weight: 365.43

Ref: TM-T11501