PI3K/HDAC-IN-1, identified by its CAS number 2361418-52-0, is a small molecule inhibitor that targets both phosphoinositide 3-kinases (PI3K) and histone deacetylases (HDACs). This dual inhibition is significant in cancer research, as it can potentially disrupt pathways that promote tumor growth and survival. The compound is characterized by its ability to modulate cellular signaling and gene expression, making it a valuable tool in the study of cancer biology and therapeutic development. Its chemical structure typically includes functional groups that facilitate interaction with the target enzymes, enhancing its efficacy. Additionally, PI3K/HDAC-IN-1 is often evaluated in preclinical studies for its pharmacological properties, including potency, selectivity, and bioavailability. Understanding its mechanism of action and biological effects is crucial for assessing its potential as a therapeutic agent in oncology and other diseases where PI3K and HDAC pathways are implicated.

PI3K/HDAC-IN-1

2361418-52-0: PI3K/HDAC-IN-1, identified by its CAS number 2361418-52-0, is a small molecule inhibitor that targets both phosphoinositide 3-kinases (PI3K) and histone deacetylases (HDACs). This dual inhibition is significant in cancer research, as it can potentially disrupt pathways that promote tumor growth and survival. The compound is characterized by its ability to modulate cellular signaling and gene expression, making it a valuable tool in the study of cancer biology and therapeutic development. Its chemical structure typically includes functional groups that facilitate interaction with the target enzymes, enhancing its efficacy. Additionally, PI3K/HDAC-IN-1 is often evaluated in preclinical studies for its pharmacological properties, including potency, selectivity, and bioavailability. Understanding its mechanism of action and biological effects is crucial for assessing its potential as a therapeutic agent in oncology and other diseases where PI3K and HDAC pathways are implicated.

<p>PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).</p>

CAS 2361418-52-0

PI3K/HDAC-IN-1

PI3K/HDAC-IN-1

Ref: TM-T12455