CAS 2361988-77-2

cRIPGBM chloride

CAS: 2361988-77-2

cRIPGBM chloride

Purity: ≥98%

Molecular weight: 446.9g/mol

Ref: 54-BUP21103

3-[(4-Fluorophenyl)methyl]-2-methyl-4,9-dioxo-1-(phenylmethyl)-1H-naphth[2,3-d]imidazolium chloride

CAS: 2361988-77-2

3-[(4-Fluorophenyl)methyl]-2-methyl-4,9-dioxo-1-(phenylmethyl)-1H-naphth[2,3-d]imidazolium chloride (IMC) is a small molecule that inhibits the autophagy pathway. Autophagy is a process by which cells break down and recycle their own components to provide energy or to eliminate toxic substances. IMC has been shown to inhibit the growth of glioma cells in tissue culture, as well as human malignant brain tumors in vivo. IMC also blocks epidermal growth factor receptor (EGFR) signaling by targeting EGFR downstream molecules such as ERK and AKT.

Formula: C₂₆H₂₀ClFN₂O₂

Purity: Min. 95%

Molecular weight: 446.9 g/mol

Ref: 3D-LUD98877

cRIPGBM chloride

CAS: 2361988-77-2

cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.

Formula: C₂₆H₂₀ClFN₂O₂

Purity: 99.75%

Color and Shape: Solid

Molecular weight: 446.9

Ref: TM-T72658