CAS 236395-14-5

Acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10(S)-yl ester

Description:

Acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10(S)-yl ester, identified by its CAS number 236395-14-5, is a chemical compound that belongs to the class of dibenzoazepines, which are characterized by their fused aromatic and heterocyclic structures. This compound features a carbamoyl group, which contributes to its potential biological activity, and an ester functional group derived from acetic acid, indicating it may have applications in medicinal chemistry. The presence of the 10(S)-yl configuration suggests stereochemical specificity, which can influence its pharmacological properties. The compound's structure may allow for interactions with biological targets, making it of interest in drug development. Additionally, its solubility and reactivity can be influenced by the functional groups present, affecting its behavior in various chemical environments. Overall, this compound's unique structural features may provide insights into its potential uses in therapeutic applications, although specific biological activities would require further investigation through experimental studies.

Formula: C₁₇H₁₆N₂O₃

InChI: InChI=1/C17H16N2O3/c1-11(20)22-16-10-12-6-2-4-8-14(12)19(17(18)21)15-9-5-3-7-13(15)16/h2-9,16H,10H2,1H3,(H2,18,21)/t16-/m0/s1

InChI key: InChIKey=QIALRBLEEWJACW-INIZCTEOSA-N

SMILES: O(C(C)=O)[C@@H]1C=2C(N(C(N)=O)C=3C(C1)=CC=CC3)=CC=CC2

Synonyms:

• (10S)-10-(Acetyloxy)-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
• (S)-(-)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
• (S)-(-)-10-Acetoxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
• (S)-5-Carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate
• 5H-Dibenz[b,f]azepine-5-carboxamide, 10-(acetyloxy)-10,11-dihydro-, (10S)-
• Aptiom
• Bia 2-093
• Eslicarbazepine Acetate
• Exalief
• Exelief
• Sep 0002093
• Zebinix
• Licarbazepine Acetate S-Isomer
• Acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10(S)-yl ester
• S(+)-10-acetoxy-10,11-Dihydro-10-5H-dibenz[b,f]azepine-5-carboxamide
• Licarbazepine Impurity 4(Licarbazepine Acetate S-Isomer)
• Eslicarbazepine acetate (racemate)
• BIA 2-093;APTIOM
• Eslicarbazepine Acetate BIA 2-093
• EslicarbazepineAcetate&gt
• Acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester
• S-Licarbazepine Acetate
• Eslicarbazepine acetate Impurity

Eslicarbazepine Acetate

CAS: 236395-14-5

Formula: C₁₇H₁₆N₂O₃

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 296.33

Ref: 3B-E1046

Eslicarbazepine Acetate

CAS: 236395-14-5

Color and Shape: Neat

Ref: 61-FOR3544.00

Eslicarbazepine Acetate

CAS: 236395-14-5

Anticonvulsants, hypnotics and sedatives

Formula: C₁₇H₁₆N₂O₃

Color and Shape: White Crystalline Powder

Molecular weight: 296.11609

Ref: 45-1249508

5H-Dibenz[b,f]azepine-5-carboxamide, 10-(acetyloxy)-10,11-dihydro-, (10S)-

CAS: 236395-14-5

Formula: C₁₇H₁₆N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 296.3205

Ref: IN-DA002NZQ

Eslicarbazepine acetate

CAS: 236395-14-5

Eslicarbazepine acetate

Purity: 98%

Molecular weight: 296.32g/mol

Ref: 54-OR1029025

(S)-Licarbazepine Acetate

CAS: 236395-14-5

Formula: C₁₇H₁₆N₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 296.33

Ref: 4Z-C-1922

Eslicarbazepine Acetate

CAS: 236395-14-5

Eslicarbazepine Acetate

Purity: ≥98%

Molecular weight: 296.32g/mol

Ref: 54-BUP15566

Eslicarbazepine Acetate

CAS: 236395-14-5

Formula: C₁₇H₁₆N₂O₃

Color and Shape: Neat

Molecular weight: 296.32

Ref: 86-MM3544.00

Eslicarbazepine Acetate

CAS: 236395-14-5

Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for partial-onset seizures.

Formula: C₁₇H₁₆N₂O₃

Purity: 99.58% - >99.99%

Color and Shape: White To Off-White Solid

Molecular weight: 296.32

Ref: TM-T3285

Eslicarbazepine Acetate

CAS: 236395-14-5

Applications Eslicarbazepine acetate, (BIA 2-093), is a promising antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine. Neuroprotective & Neuroresearch product.
References Benes, J., et al.: J. Med. Chem., 42, 2582 (1999), Tong, X., et al.: Br. J. Pharmacol., 133, 867 (2001), Almeida, L., et al.: J. Clin. Pharmacol., 45, 1062 (2005), Elger, C., et al.: Epilepsia, 48, 497 (2007),

Formula: C₁₇H₁₆N₂O₃

Color and Shape: White To Light Brown

Molecular weight: 296.32

Ref: TR-E659000

Eslicarbazepine acetate

CAS: 236395-14-5

Eslicarbazepine acetate is an anticonvulsant drug that has been shown to be effective in reducing the frequency of seizures. It is a prodrug and is metabolized by esterases to form the active form, eslicarbazepin acetate. Eslicarbazepine acetate inhibits glutamate release by acting on the glutamate transporter, which prevents depolarization of the mitochondrial membrane potential, leading to inhibition of epileptic activity. Eslicarbazepine acetate also decreases brain levels of GABA and increases levels of polyamines such as spermidine and spermine, which are neuroprotective. There are some reports of hepatic impairment when eslicarbazepine acetate is used with other drugs that are metabolized through this organ (e.g., valproic acid).
Eslicarbazepine acetate can cause chemical stability issues when exposed to light or air due to oxidation reactions. It may also react

Formula: C₁₇H₁₆N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 296.32 g/mol

Ref: 3D-FE22807

(S)-5-Carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate

CAS: 236395-14-5

Formula: C₁₇H₁₆N₂O₃

Purity: 98%+;RG

Molecular weight: 296.326

Ref: 10-F463334

Eslicarbazepine Acetate-D3

Controlled Product

CAS: 236395-14-5

Applications Eslicarbazepine acetate-D3 is a labelled analogue of Eslicarbazepine acetate (E659000), a voltage-gated sodium channel blocker and antiepileptic that is used to treat patients with epilepsy.
References Almeida, L., et al.: Eur. J. Clin. Pharmacol., 64, 267 (2008); Gil-Nagel, A., et al.: Acta Neurol. Scand., 120, 281 (2009); McCormack, P. & Robinson, D.: CNS Drugs, 23, 71 (2009)

Formula: C₁₇H₁₃D₃N₂O₃

Color and Shape: Neat

Molecular weight: 299.34

Ref: TR-E659002