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CAS 23640-96-2

:

6α,9-difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 17-butyrate

Description:
6α,9-Difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 17-butyrate, commonly known as a synthetic corticosteroid, is characterized by its complex steroid structure, which includes multiple hydroxyl groups and fluorine substitutions. This compound is derived from the natural steroid backbone of pregnenolone, modified to enhance its pharmacological properties. The presence of fluorine atoms typically increases the compound's potency and metabolic stability. The hydroxyl groups contribute to its solubility and interaction with biological receptors, particularly the glucocorticoid receptor, which mediates anti-inflammatory and immunosuppressive effects. The butyrate ester enhances the lipophilicity of the molecule, potentially improving its absorption and bioavailability. This compound is primarily used in therapeutic applications, particularly in the treatment of inflammatory conditions and certain autoimmune disorders. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are influenced by its structural modifications, making it an important agent in clinical settings. As with all corticosteroids, careful consideration of dosage and potential side effects is essential in its use.
Formula:C25H32F2O6
InChI:InChI=1/C25H32F2O6/c1-4-5-21(32)33-24(20(31)13-28)9-7-15-16-11-18(26)17-10-14(29)6-8-22(17,2)25(16,27)19(30)12-23(15,24)3/h6,8,10,15-16,18-19,28,30H,4-5,7,9,11-13H2,1-3H3
InChI key:InChIKey=BQEJAAIPKDQEPV-MXHGPKCJSA-N
SMILES:O(C(CCC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](CC1)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[H])[H]
Synonyms:
  • (6α,11β)-6,9-Difluoro-11,21-dihydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dione
  • 6,9-Difluoro-11,21-Dihydroxy-3,20-Dioxopregna-1,4-Dien-17-Yl Butanoate
  • 6α,9-Difluoroprednisolone 17-butyrate
  • Butyric acid, 17-ester with 6α,9-difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione
  • Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,21-dihydroxy-17-(1-oxobutoxy)-, (6α,11β)-
  • Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-, 17-butyrate
  • 6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17-butyrate
  • 6α,9α-Difluoroprednisolone-17-butyrate
  • Einecs 245-798-3
  • 21-Desacetyl Difluprednate-d5
  • See more synonyms
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