CAS 236403-25-1

3-Isoquinolinecarboxamide,1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-

Description:

3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-, identified by CAS number 236403-25-1, is a chemical compound characterized by its complex structure, which includes an isoquinoline core and a sulfonamide group. This compound features a tetrahydroisoquinoline moiety, indicating it has undergone hydrogenation, resulting in a saturated ring structure. The presence of a hydroxyl group (N-hydroxy) suggests potential reactivity and biological activity, possibly influencing its pharmacological properties. The methoxyphenylsulfonyl group enhances its solubility and may contribute to its interaction with biological targets. Compounds of this nature are often investigated for their potential therapeutic applications, particularly in the fields of medicinal chemistry and drug development. The stereochemistry indicated by (3R)- suggests specific spatial arrangements that can significantly affect the compound's biological activity and interactions. Overall, this compound exemplifies the intricate design often found in drug candidates, combining various functional groups that may confer unique properties.

Formula: C₁₇H₁₈N₂O₅S

Synonyms:

• (3R)-(+)-[2-(4-METHOXYBENZENESULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-HYDROXAMATE]
• 3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-
• MMP-8 INHIBITOR I
• MMP 8-I

MMP-8 Inhibitor I

CAS: 236403-25-1

Formula: C₁₇H₁₈N₂O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 362.4002

Ref: IN-DA00BER6

MMP-8 Inhibitor I

CAS: 236403-25-1

MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.

Formula: C₁₇H₁₈N₂O₅S

Color and Shape: Solid

Molecular weight: 362.4

Ref: TM-T69666

MMP-8 Inhibitor I

CAS: 236403-25-1

Formula: C₁₇H₁₈N₂O₅S

Molecular weight: 362.40

Ref: 4Z-M-178003

MMP 8-I

Controlled Product

CAS: 236403-25-1

Applications MMP 8-I is a matrix metalloproteinase 8 inhibitor. Matrix metalloproteinases are involved with tight junction protein degradation in endothelial cells.
References Kumar, H., et al.: Mol Neurobiol. (2017)

Formula: C₁₃H₁₂N₄O₂S

Color and Shape: Neat

Molecular weight: 288.325

Ref: TR-M425440

MMP-8 Inhibitor I

CAS: 236403-25-1

Formula: C₁₇H₁₈N₂O₅S

Molecular weight: 362.4

Ref: ST-EA-CP-M226006