CAS 23642-66-2

Benfluorex hydrochloride

Description:

Benfluorex hydrochloride is a synthetic compound primarily used as an anti-obesity medication and has been associated with the treatment of metabolic disorders. It is a derivative of fenfluramine and acts as a serotonin receptor agonist, influencing appetite regulation and energy expenditure. The substance is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a moderate stability profile under standard conditions. Its chemical structure includes a fluorinated phenyl ring, contributing to its pharmacological properties. Benfluorex hydrochloride has been noted for its potential side effects, including cardiovascular issues, which led to its withdrawal from several markets. As with many pharmaceuticals, its use requires careful consideration of dosage and patient health status, and it is subject to regulatory scrutiny. Overall, while it has therapeutic applications, the safety profile and regulatory status of benfluorex hydrochloride necessitate cautious use and ongoing evaluation in clinical settings.

Formula: C₁₉H₂₀F₃NO₂·ClH

InChI: InChI=1S/C19H20F3NO2.ClH/c1-14(12-15-6-5-9-17(13-15)19(20,21)22)23-10-11-25-18(24)16-7-3-2-4-8-16;/h2-9,13-14,23H,10-12H2,1H3;1H

InChI key: InChIKey=NLOALSPYZIIXEO-UHFFFAOYSA-N

SMILES: C(C(NCCOC(=O)C1=CC=CC=C1)C)C2=CC(C(F)(F)F)=CC=C2.Cl

Synonyms:

• (±)-N-(2-Benzoyloxyethyl)norfenfluramine hydrochloride
• 2-((1-Methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)ethyl benzoate hydrochloride
• 2-((alpha-Methyl-m-(trifluoromethyl)phenethyl)amino)ethanol benzoate (ester)
• 2-(-Methyl-3-(trifluoromethyl)phenethylamino)ethyl benzoate hydrochloride
• 2-(alpha-Methyl-3-(trifluoromethyl)phenylethylamino)ethyl benzoat
• 2-({1-[3-(Trifluoromethyl)Phenyl]Propan-2-Yl}Amino)Ethyl Benzoate Hydrochloride (1:1)
• Balans
• Benfluorex HCl
• Ethanol, 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-, benzoate (ester), hydrochloride
• Ethanol, 2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)-, benzoate (ester), HCl
• Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, 1-benzoate, hydrochloride (1:1)
• Ethanol, 2-[[α-methyl-m-(trifluoromethyl)phenethyl]amino]-, benzoate (ester), hydrochloride
• Jp 992
• Lipophoral
• Mediator
• Mediaxal
• S 992
• Unii-X7O165Xz00
• Benfluorex hydrochloride

2-((1-(3-(Trifluoromethyl)phenyl)propan-2-yl)amino)ethyl benzoate hydrochloride

CAS: 23642-66-2

Formula: C₁₉H₂₁ClF₃NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 387.8237

Ref: IN-DA002O0S

2-({1-[3-(Trifluoromethyl)phenyl]prop-2-yl}amino)ethyl benzoate hydrochloride

CAS: 23642-66-2

2-({1-[3-(Trifluoromethyl)phenyl]prop-2-yl}amino)ethyl benzoate hydrochloride

Purity: ≥95%

Molecular weight: 387.82g/mol

Ref: 54-PC8120

Benfluorex hydrochloride

Controlled Product

CAS: 23642-66-2

Formula: C₁₉H₂₁ClF₃NO₂

Color and Shape: Neat

Molecular weight: 387.82

Ref: 04-C10469000

Benfluorex Hydrochloride

Controlled Product

CAS: 23642-66-2

Applications Used as an antihyperlipoproteinemic therapeutic.
References Beckett, A.H., et al.: J. Pharm. Pharmacol., 23, 950 (1971), Brindley, D.N., et al.: J. Pharm. Pharmacol., 28, 670 (1976)

Formula: C₁₉H₂₁ClF₃NO₂

Color and Shape: White Solid

Molecular weight: 387.82

Ref: TR-B135000

Benfluorex hydrochloride

Controlled Product

CAS: 23642-66-2

Benfluorex hydrochloride is a fluorinated derivative of benfluorex, which is an experimental drug for the treatment of bone cancer. It was shown to be effective in treating bowel disease, primary pulmonary hypertension and carcinoid syndrome in animal models. Benfluorex hydrochloride inhibits the activity of enzymes that are involved in the metabolism of carbohydrates and lipids. It has been shown to increase uric acid levels and inhibit the activity of enzymes that are involved in the synthesis of amino acids. This leads to cell lysis and an increased production of glucose-6-phosphate. The use of benfluorex hydrochloride as a diagnostic tool has been studied extensively, with its most notable application being its use as a marker for group P2 enzyme activities.

Formula: C₁₉H₂₀F₃NO₂•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 387.82 g/mol

Ref: 3D-FB103383