Fmoc-Gly-Gly-Phe-OtBu is a protected peptide derivative commonly used in peptide synthesis and research. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino terminus, allowing for selective coupling reactions without interference. The sequence includes two glycine (Gly) residues and one phenylalanine (Phe) residue, contributing to its structural and functional properties. The "OtBu" (tert-butyl) group is a protecting group for the carboxylic acid functionality, enhancing the stability and solubility of the compound during synthesis. This peptide is typically utilized in solid-phase peptide synthesis (SPPS), where the protection and deprotection strategies are crucial for the successful assembly of peptides. The compound's characteristics include its ability to form secondary structures, potential for biological activity, and its role in studying peptide interactions and functions. Overall, Fmoc-Gly-Gly-Phe-OtBu is an important intermediate in the synthesis of more complex peptides and can be utilized in various biochemical applications.

Fmoc-Gly-Gly-Phe-OtBu

236426-37-2: Fmoc-Gly-Gly-Phe-OtBu is a protected peptide derivative commonly used in peptide synthesis and research. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino terminus, allowing for selective coupling reactions without interference. The sequence includes two glycine (Gly) residues and one phenylalanine (Phe) residue, contributing to its structural and functional properties. The "OtBu" (tert-butyl) group is a protecting group for the carboxylic acid functionality, enhancing the stability and solubility of the compound during synthesis. This peptide is typically utilized in solid-phase peptide synthesis (SPPS), where the protection and deprotection strategies are crucial for the successful assembly of peptides. The compound's characteristics include its ability to form secondary structures, potential for biological activity, and its role in studying peptide interactions and functions. Overall, Fmoc-Gly-Gly-Phe-OtBu is an important intermediate in the synthesis of more complex peptides and can be utilized in various biochemical applications.

<p>Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker. Fmoc-Gly-Gly-Phe-OtBu can be used in the synthesis of antibody-drug conjugates (ADCs).</p>

CAS 236426-37-2

Fmoc-Gly-Gly-Phe-OtBu

Fmoc-Gly-Gly-Phe-OtBu

Ref: 54-BUP10184

Fmoc-Gly-Gly-Phe-OtBu

Ref: TM-T17953