CAS 2365-44-8

Isatin hydrazone

Description:

Isatin hydrazone is an organic compound derived from isatin, which is a diketopiperazine. It is characterized by the presence of a hydrazone functional group, formed through the reaction of isatin with hydrazine or its derivatives. This compound typically appears as a crystalline solid and exhibits a range of interesting properties, including potential biological activity. Isatin hydrazone is known for its ability to act as a ligand in coordination chemistry and has been studied for its applications in medicinal chemistry, particularly for its antimicrobial and anticancer properties. The compound may also display various physical properties such as solubility in organic solvents and moderate stability under standard conditions. Its reactivity can be influenced by the presence of substituents on the isatin moiety, which can affect its biological interactions and chemical behavior. Overall, isatin hydrazone serves as a valuable compound in both synthetic and pharmaceutical chemistry, warranting further exploration of its properties and applications.

Formula: C₈H₇N₃O

InChI: InChI=1S/C8H7N3O/c9-11-7-5-3-1-2-4-6(5)10-8(7)12/h1-4H,9H2,(H,10,11,12)

InChI key: InChIKey=WXUKYQGOSKSDRP-UHFFFAOYSA-N

SMILES: N(N)=C1C=2C(NC1=O)=CC=CC2

Synonyms:

• Indole-2,3-dione, hydrazone
• 1H-Indole-2,3-dione, 3-hydrazone
• Isatin β-hydrazone
• Isatin 3-hydrazone
• Indole-2,3-dione, 3-hydrazone

3-Hydrazonoindolin-2-one

CAS: 2365-44-8

Formula: C₈H₇N₃O

Purity: 95%

Molecular weight: 161.1607

Ref: IN-DA002O1D

Sunitinib Impurity 34

CAS: 2365-44-8

Formula: C₈H₇N₃O

Molecular weight: 161.16

Ref: 4Z-S-4148

2-oxoindoline-3-hydrazone

CAS: 2365-44-8

2-Oxoindoline-3-hydrazone (2OIH) is a heterocyclic compound that has been reported to have anticancer activity. 2OIH is an intramolecular hydrogen bond acceptor, which may account for its anticancer activity. It has been shown to be effective against cancer cells in mammalian cell lines and in vitro studies of human carcinoma cell lines. This compound also showed anticancer activity against bacteria such as Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus). The geometric isomers of 2OIH have been studied using nmr spectra, and the carbonyl group has been identified as the source of its anti-cancer properties. Structural analysis has revealed that the hydroxyl group on the indole moiety is important for the anti-cancer properties of this molecule.

Formula: C₈H₇N₃O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 161.16 g/mol

Ref: 3D-FO169126