CAS 23674-86-4

Epitopic

Description:

Epitopic, with the CAS number 23674-86-4, is a chemical substance that is primarily recognized for its role in immunology rather than as a standalone chemical compound. The term "epitope" refers to the specific part of an antigen that is recognized by the immune system, particularly by antibodies, T-cell receptors, or B-cell receptors. Epitopes can be linear or conformational and are crucial for the specificity of immune responses. In the context of research and therapeutic applications, substances associated with epitopes may be involved in vaccine development, diagnostics, and the study of autoimmune diseases. The characteristics of such substances typically include their ability to elicit an immune response, their structural diversity, and their potential for modification to enhance immunogenicity. While the specific properties of Epitopic as a chemical entity may not be widely documented, its relevance in biological and medical fields underscores the importance of understanding epitopes in the context of immune system interactions.

Formula: C₂₇H₃₄F₂O₇

InChI: InChI=1S/C27H34F2O7/c1-5-6-23(34)36-26(22(33)14-35-15(2)30)10-8-17-18-12-20(28)19-11-16(31)7-9-24(19,3)27(18,29)21(32)13-25(17,26)4/h7,9,11,17-18,20-21,32H,5-6,8,10,12-14H2,1-4H3/t17-,18-,20-,21-,24-,25-,26-,27-/m0/s1

InChI key: InChIKey=WYQPLTPSGFELIB-JTQPXKBDSA-N

SMILES: C(COC(C)=O)(=O)[C@]1(OC(CCC)=O)[C@]2(C)[C@@](CC1)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[H])[H]

Synonyms:

• (6Alpha,11Beta)-21-(Acetyloxy)-6,9-Difluoro-11-Hydroxy-3,20-Dioxopregna-1,4-Dien-17-Yl Butanoate
• (6Alpha,8Xi,10Xi,11Beta,13Xi)-21-(Acetyloxy)-6,9-Difluoro-11-Hydroxy-3,20-Dioxopregna-1,4-Dien-17-Yl Butanoate
• (6α,11β)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dione
• 21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dione (6alpha,11beta)-
• 6-Alpha,9α-difluoroprednisolone 21-acetate 17-butyrate
• 6-alpha,9-alpha-Difluoroprednisolone 17-butyrate 21-acetate
• 6a,9-Difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-butyrate
• 6alpha,9-Difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-butyrate
• 6alpha-9-Difluoroprednisolone 21-acetate 17-butyrate
• 6α,9-Difluoroprednisolone 21-acetate 17-butyrate
• 6α,9α-Difluoroprednisolone 21-acetate 17-butyrate
• Butyric acid, 17-ester with 6α,9-difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate
• Cm 9155
• Difluprednato
• Difluprednato [INN-Spanish]
• Difluprednatum
• Difluprednatum [INN-Latin]
• Durezol
• Epitopic
• Myser
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-, (6alpha,11beta)-
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-, (6α,11β)-
• Pregna-1,4-diene-3,20-dione, 6-alpha,9-difluoro-11-beta,17,21-trihydroxy-, 21-acetate, 17-butyrate
• Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-, 21-acetate 17-butyrate
• Unii-S8A06Qg2Qe
• W 6309

(6α,11β)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dion

CAS: 23674-86-4

Formula: C₂₇H₃₄F₂O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 508.5515

Ref: IN-DA0039MA

Difluprednate

CAS: 23674-86-4

Difluprednate

Purity: 98%

Molecular weight: 508.55g/mol

Ref: 54-PC108895

Difluprednate

CAS: 23674-86-4

Formula: C₂₇H₃₄F₂O₇

Color and Shape: White To Off-White Solid

Molecular weight: 508.56

Ref: 4Z-D-125001

Difluprednate

CAS: 23674-86-4

Formula: C₂₇H₃₄F₂O₇

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 508.55

Ref: 7W-GP3988

Difluprednate

CAS: 23674-86-4

Difluprednate

Purity: ≥98%

Molecular weight: 508.55g/mol

Ref: 54-BUP17800

Difluprednate-d3

CAS: 23674-86-4

Formula: C₂₇H₃₁D₃F₂O₇

Color and Shape: White To Off-White Solid

Molecular weight: 511.58

Ref: 4Z-D-125003

Difluprednate

CAS: 23674-86-4

Formula: C₂₇H₃₄F₂O₇

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 508.56

Ref: 3B-D5579

Difluprednate

Controlled Product

CAS: 23674-86-4

Formula: C₂₇H₃₄F₂O₇

Color and Shape: White

Molecular weight: 508.55

Ref: 86-MM3567.00

Difluprednate-d5

CAS: 23674-86-4

Formula: C₂₇H₂₉F₂O₇D₅

Molecular weight: 513.59

Ref: 4Z-D-125012

Difluprednate

CAS: 23674-86-4

Difluprednate (Myser)(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.

Formula: C₂₇H₃₄F₂O₇

Purity: 99.23% - 99.86%

Color and Shape: Solid

Molecular weight: 508.55

Ref: TM-T6472

Difluprednate

Controlled Product

CAS: 23674-86-4

Applications A corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.
References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002), Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003), Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005),

Formula: C₂₇H₃₄F₂O₇

Color and Shape: White

Molecular weight: 508.55

Ref: TR-D445925

Difluprednate-d3

Controlled Product

CAS: 23674-86-4

Formula: C₂₇D₃H₃₁F₂O₇

Color and Shape: Neat

Molecular weight: 511.57

Ref: TR-D445927

Difluprednate

Controlled Product

CAS: 23674-86-4

Difluprednate is a corticosteroid that is used topically to treat eye inflammation. It has been shown to reduce ocular inflammation in rats and mice, with no effect on the cornea. Difluprednate is prepared as an aqueous solution containing benzalkonium chloride, which acts as a preservative. The medication can be used for short periods of time, but prolonged use may lead to bowel disease and polymerase chain reactions. Difluprednate has anti-inflammatory activity and can be used in place of nonsteroidal anti-inflammatory drugs (NSAIDs). It has been found that prednisolone acetate, the active form of difluprednate, inhibits inflammatory cells in vitro by inhibiting nuclear factor kappaB activation. This inhibition leads to decreased production of pro-inflammatory cytokines and chemokines such as IL-1β, IL-6, IL-8, T

Formula: C₂₇H₃₄F₂O₇

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 508.55 g/mol

Ref: 3D-FD21894

Difluprednate

CAS: 23674-86-4

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₇H₃₄F₂O₇

Molecular weight: 508.22726

Ref: 45-1197583