CAS 2369979-67-7

5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-ethyl-1-piperazinyl)-1-fluoro-

Description:

5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-ethyl-1-piperazinyl)-1-fluoro- is a chemical compound characterized by its complex bicyclic structure, which includes a diazepine core fused with two benzene rings. This compound features a chlorine atom at the 8-position and a fluoro group at the 1-position, contributing to its unique reactivity and potential biological activity. The presence of a piperazine moiety at the 11-position enhances its pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of psychoactive or therapeutic agents. The molecular structure suggests potential interactions with neurotransmitter systems, which may lead to anxiolytic or antidepressant effects. Its CAS number, 2369979-67-7, allows for precise identification in chemical databases. As with many compounds in this class, understanding its solubility, stability, and reactivity under various conditions is crucial for applications in research and development. Safety and handling considerations are also important due to the presence of halogen substituents, which can influence toxicity and environmental impact.

Formula: C₁₉H₂₀ClFN₄

Synonyms:

• 8-chloro-11-(4-ethyl-1-piperazinyl)-1-fluoro-5H-Dibenzo[b,e][1,4]diazepine
• 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-ethyl-1-piperazinyl)-1-fluoro-

JHU 37152

CAS: 2369979-67-7

Formula: C₁₉H₂₀ClFN₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 358.8403

Ref: IN-DA01LPXF

JHU37152

CAS: 2369979-67-7

JHU37152

Purity: ≥98%

Molecular weight: 358.84g/mol

Ref: 54-BUP09882

JHU37152

CAS: 2369979-67-7

JHU37152 is a DREADD agonist; Ki: 1.8 nM at hM3Dq, 8.7 nM at hM4Di; EC50: 5 nM (hM3Dq), 0.5 nM (hM4Di) in HEK-293 cell assays.

Formula: C₁₉H₂₀ClFN₄

Purity: 99.72%

Color and Shape: Solid

Molecular weight: 358.84

Ref: TM-T9019

JHU37152

CAS: 2369979-67-7

JHU37152 is a potent cyclin-dependent kinase (CDK) inhibitor that has shown promise in the treatment of leukemia and other types of cancer. It is an analog of a natural compound found in Chinese medicinal plants and has been shown to inhibit the growth of human cancer cells by inducing apoptosis, or programmed cell death. JHU37152 specifically targets CDKs, which are enzymes that regulate the cell cycle and are often overexpressed in tumor cells. By inhibiting CDK activity, this compound can halt the progression of cancer cells and prevent them from dividing. JHU37152 is a promising new class of anti-cancer drugs that may have significant therapeutic potential for treating a variety of cancer types.

Formula: C₁₉H₂₀ClFN₄

Purity: Min. 95%

Molecular weight: 358.8 g/mol

Ref: 3D-UUD97967