CAS 23736-58-5

Cloxacillin benzathine

Description:

Cloxacillin benzathine is a semi-synthetic antibiotic belonging to the penicillin class, specifically designed to combat bacterial infections. It is a combination of cloxacillin, which is effective against penicillinase-producing staphylococci, and benzathine, which serves as a long-acting vehicle for the drug. This formulation allows for prolonged therapeutic effects, making it suitable for treating infections that require sustained antibiotic levels in the bloodstream. Cloxacillin benzathine is typically administered via intramuscular injection and is used to treat various infections, including skin and soft tissue infections, respiratory tract infections, and certain types of endocarditis. The compound exhibits characteristics typical of beta-lactam antibiotics, including the ability to inhibit bacterial cell wall synthesis, leading to cell lysis and death. It is important to note that, like other penicillins, it may cause allergic reactions in some individuals. Proper storage conditions and adherence to dosage guidelines are essential to ensure its efficacy and safety.

Formula: C₁₉H₁₈ClN₃O₅SC₁₆H₂₀N₂

InChI: InChI=1S/C19H18ClN3O5S.C16H20N2/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);1-10,17-18H,11-14H2/t13-,14+,17-;/m1./s1

InChI key: InChIKey=OUMOALQYXBRQFX-SLINCCQESA-N

SMILES: C(NCCNCC1=CC=CC=C1)C2=CC=CC=C2.N(C(=O)C=1C(=NOC1C)C2=C(Cl)C=CC=C2)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H]

Synonyms:

• (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine (2:1)
• 1,2-Ethanediamine, N,N′-bis(phenylmethyl)-, bis[(2S,5R,6R)-6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-1-carboxylate]
• 1,2-Ethanediamine, N,N′-bis(phenylmethyl)-, bis[[2S-(2α,5α,6β)]-6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-1-carboxylate]
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-, compd. with N,N′-dibenzylethylenediamine (2:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-, compd. with N,N′-bis(phenylmethyl)-1,2-ethanediamine (2:1)
• 6-({[3-(2-Chlorophenyl)-5-Methyl-1,2-Oxazol-4-Yl]Carbonyl}Amino)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid
• Benzathine cloxacillin
• Boviclox
• Cloxacillin benzathin
• Cloxacillin benzathine
• Dry-Clox
• Ethylenediamine, N,N′-dibenzyl-, bis[6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-1-carboxylate]
• Ethylenediamine, N,N′-dibenzyl-, bis[6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]
• Noroclox DC
• Opticlox
• Orbenin Dry Cow
• Triclox

Cloxacillin benzathine

CAS: 23736-58-5

Cloxacillin benzathine

Formula: C₁₆H₂₀N₂(C₁₉H₁₈CIN₃O₅S)₂

Purity: 95.5%

Color and Shape: White

Molecular weight: 1318.16503

Ref: 47-88

Cloxacillin Benzathine

CAS: 23736-58-5

Penicillins and their derivatives with a penicillanic a

Formula: C₁₉H₁₈ClN₃O₅SC₁₆H₂₀N₂

Color and Shape: White Powder

Molecular weight: 1112.11

Ref: 45-1141909

Cloxacillin Benzathine

CAS: 23736-58-5

Formula: C₁₉H₁₇ClN₃O₅S·Na·C₁₆H₂₀N₂

Molecular weight: 434.87 22.99 240.35

Ref: 4Z-C-191017

Cloxacillin Benzathine (2:1)

Controlled Product

CAS: 23736-58-5

Applications Cloxacillin Benzathine is a salt of Cloxacillin is an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.
References Gibbs, D.L. et al.: Curr. Microbiol., 2, 239 (1979); Dmitrova, D. et al.: Farmat., 48, 28 (2001); CRaven, N. et al.: Res. Vet. Sci., 29, 57 (1980);

Formula: C₁₉H₁₈ClN₃O₅S·C₁₆H₂₀N₂

Color and Shape: Neat

Molecular weight: 1112.11

Ref: TR-C587465

Cloxacillin benzathine

CAS: 23736-58-5

Cloxacillin benzathine is a beta-lactam antibiotic, which is synthesized from Penicillium fungi-derived penicillins. It acts by inhibiting bacterial cell wall synthesis. The mechanism involves the irreversible inhibition of penicillin-binding proteins (PBPs). This disruption in the bacterial cell wall structure ultimately leads to cell lysis and death.

Formula: C₅₄H₅₆Cl₂N₈O₁₀S₂

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 1,112.11 g/mol

Ref: 3D-FC171054

Cloxacillin Benzathine

CAS: 23736-58-5

Formula: C₁₉H₁₈ClN₃O₅SC₁₆H₂₀N₂

Molecular weight: 2(435.88) : 240.35

Ref: ST-EA-CP-C155018