CAS 2374-03-0

4-Amino-3-hydroxybenzoic acid

Description:

4-Amino-3-hydroxybenzoic acid, also known as para-aminosalicylic acid (PAS), is an aromatic compound characterized by the presence of both an amino group (-NH2) and a hydroxyl group (-OH) on a benzene ring, specifically at the 4 and 3 positions, respectively. This compound is a white to off-white crystalline powder that is soluble in water and exhibits weak acidity due to the carboxylic acid functional group (-COOH) present in its structure. It has been utilized primarily in the pharmaceutical industry, particularly as an anti-tuberculosis agent, due to its ability to inhibit bacterial growth. The presence of the amino and hydroxyl groups contributes to its biological activity and makes it a valuable compound in medicinal chemistry. Additionally, 4-amino-3-hydroxybenzoic acid can participate in various chemical reactions, including acylation and diazotization, which are important for synthesizing other organic compounds. Its safety profile indicates that it should be handled with care, as with many chemical substances.

Formula: C₇H₇NO₃

InChI: InChI=1/C7H7NO3/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,9H,8H2,(H,10,11)

InChI key: NFPYJDZQOKCYIE-UHFFFAOYSA-N

SMILES: c1cc(c(cc1C(=O)O)O)N

Synonyms:

• 3-Hydroxy-4-aminobenzoic acid
• 4-AMINO-3-HYDROXYBENZOIC ACID 97%
• BENZOIC ACID, 4-AMINO-3-HYDROXY-
• 3-Hydroxy PABA
• 4-AMINO-3-HYDROXYBENZOIC ACID

4-Amino-3-hydroxybenzoic Acid

CAS: 2374-03-0

Formula: C₇H₇NO₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Brown powder to crystal

Molecular weight: 153.14

Ref: 3B-A1194

4-Amino-3-hydroxybenzoic acid, 98%

CAS: 2374-03-0

4-Amino-3-hydroxybenzoic acid is used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy

Formula: C₇H₇NO₃

Purity: 98%

Color and Shape: Dark cream to cream to brown, Powder

Molecular weight: 153.14

Ref: 02-A10207

4-Amino-3-hydroxybenzoic Acid

CAS: 2374-03-0

Formula: C₇H₇NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 153.1354

Ref: IN-DA0033WC

4-Amino-3-hydroxybenzoic acid

CAS: 2374-03-0

4-Amino-3-hydroxybenzoic acid

Formula: C₇H₇NO₃

Purity: ≥95%

Color and Shape: white to beige Solid

Molecular weight: 153.13538

Ref: 54-OR2857

4-Amino-3-hydroxybenzoic acid

CAS: 2374-03-0

Formula: C₇H₇NO₃

Molecular weight: 153.14

Ref: 7W-GM8169

Oxybuprocaine EP Impurity C

CAS: 2374-03-0

Formula: C₇H₇NO₃

Color and Shape: Neat

Molecular weight: 153.14

Ref: 86-MM0543.03

Tafamidis Impurity 11

CAS: 2374-03-0

Formula: C₇H₇NO₃

Molecular weight: 153.14

Ref: 4Z-T-302016

4-Amino-3-hydroxybenzoic Acid

Controlled Product

CAS: 2374-03-0

Applications 4-Amino-3-hydroxybenzoic Acid is disubsituted benzoic acid used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors.
References Kono, K. et al.: J. Antibiot., 53, 759 (2000);

Formula: C₇H₇NO₃

Color and Shape: Neat

Molecular weight: 153.14

Ref: TR-A611215

4-Amino-3-hydroxybenzoic acid

CAS: 2374-03-0

4-Amino-3-hydroxybenzoic acid is a small molecule that has been shown to inhibit the activity of epidermal growth factor receptor (EGFR) and human epidermal growth factor (HER2). It is also an inhibitor of cytochrome P450 enzymes, which are involved in the metabolism of drugs. 4-Amino-3-hydroxybenzoic acid is used in vitro as an antifungal agent for Candida albicans and other pathogenic fungi. This drug inhibits the growth of cancer cells by binding to specific cell surface receptors, causing them to detach from their surroundings and die. 4-Amino-3-hydroxybenzoic acid may have potential as a drug for treating metastatic colorectal cancer. The mechanism of action is not yet fully understood but it may be related to the inhibition of intermolecular hydrogen bonding and water permeability.

Formula: C₇H₇NO₃

Purity: Min. 97.5 Area-%

Color and Shape: Off-White Powder

Molecular weight: 153.14 g/mol

Ref: 3D-FA31608

4-Amino-3-hydroxybenzoic acid

CAS: 2374-03-0

4-Amino-3-hydroxybenzoic acid

Formula: C₇H₇NO₃

Purity: 98%

Molecular weight: 153.14

Ref: IN-DG4860

4-Amino-3-hydroxybenzoic acid

CAS: 2374-03-0

Formula: C₇H₇NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 153.137

Ref: 10-F065683

Tafamidis Impurity 8

CAS: 2374-03-0

Formula: C₇H₇NO₃

Molecular weight: 153.1

Ref: ST-EA-CP-T108009