CAS 237430-03-4: Alsterpaullone

Description: Alsterpaullone is a synthetic compound that belongs to the class of small molecules known as cyclin-dependent kinase (CDK) inhibitors. It is characterized by its ability to selectively inhibit CDK2, which plays a crucial role in cell cycle regulation. This inhibition can lead to cell cycle arrest, making Alsterpaullone a subject of interest in cancer research, as it may help in controlling the proliferation of cancer cells. The compound has a unique chemical structure that includes a bicyclic core, contributing to its biological activity. Alsterpaullone is typically studied in the context of its potential therapeutic applications, particularly in oncology, where targeting CDKs can be a strategy for cancer treatment. Additionally, it has been used in various biochemical assays to explore the mechanisms of cell cycle regulation and the effects of CDK inhibition on cellular processes. As with many chemical substances, handling Alsterpaullone requires appropriate safety measures due to its biological activity and potential toxicity.

Formula: C₁₆H₁₁N₃O₃

InChI: InChI=1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20)

InChI key: InChIKey=OLUKILHGKRVDCT-UHFFFAOYSA-N

SMILES: O=C1NC=2C=CC=CC2C=3NC=4C=CC(=CC4C3C1)N(=O)=O

Synonyms:

• 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one
• 9-Nitropaullone
• Alsterpaullone
• Indolo[3,2-d][1]benzazepin-6(5H)-one, 7,12-dihydro-9-nitro-
• Nsc-705701

ALSTERPAULLONE

CAS: 237430-03-4

• Formula: C₁₆H₁₃N₃O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 295.2927

ALSTERPAULLONE

CAS: 237430-03-4

• Purity: 99.39%
• Molecular weight: 293.28g/mol

7,12-Dihydro-9-Nitroindolo[3,2-D][1]Benzazepin-6(5H)-One

CAS: 237430-03-4

• Purity: 98%
• Molecular weight: 293.28g/mol

ALSTERPAULLONE

CAS: 237430-03-4

Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec

• Formula: C₁₆H₁₁N₃O₃
• Purity: 99.39%
• Color and Shape: Solid
• Molecular weight: 293.28

Alsterpaullone

CAS: 237430-03-4

• Formula: C₁₆H₁₁N₃O₃
• Purity: ≥ 98.0%
• Color and Shape: Yellow to brown powder
• Molecular weight: 293.28

Alsterpaullone

CAS: 237430-03-4

• Formula: C₁₆H₁₁N₃O₃
• Color and Shape: Neat
• Molecular weight: 293.277

Alsterpaullone

CAS: 237430-03-4

Alsterpaullone is a cytotoxic drug that inhibits the mitochondrial membrane potential by blocking the respiratory …

• Formula: C₁₆H₁₁N₃O₃
• Purity: Min. 95%
• Molecular weight: 293.28 g/mol