CAS 2374782-04-2

(S)-2,2',2''-(10-(2-(4-(3-((4-((2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)(methyl)amino)propyl)piperazin-1-yl)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)t

CAS: 2374782-04-2

(S)-2,2',2''-(10-(2-(4-(3-((4-((2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)(methyl)amino)propyl)piperazin-1-yl)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)t

Purity: 98%

Molecular weight: 885.97g/mol

Ref: 54-PC1005769

FAPI-46

CAS: 2374782-04-2

FAPI-46 is a radiotracer for fibroblast activation protein (FAP),conjugated with 68Ga or 177Lu tracer for FAP tumours in positron emission tomography (PET).

Formula: C₄₁H₅₇F₂N₁₁O₉

Color and Shape: Solid

Molecular weight: 885.96

Ref: TM-T39922

FAPI-46

CAS: 2374782-04-2

A quinoline-based fibroblast activation protein (FAP) targeted radiotracer

Formula: C₄₁H₅₇F₂N₁₁O₉

Purity: Min. 95%

Molecular weight: 885.96 g/mol

Ref: 3D-ZUD78204

FAPI-46 trifluoroacetate

CAS: 2374782-04-2

FAPI-46 trifluoroacetate is a fibroblast activation protein (FAP) inhibitor, which is synthesized as part of targeted cancer research efforts. It is derived from chemical engineering processes focusing on the modification of small molecules to selectively interact with FAP, an enzyme overexpressed in cancer-associated fibroblasts (CAFs) within the tumor microenvironment. FAPI-46 binds to and inhibits FAP, reducing its enzymatic activity. By blocking FAP, FAPI-46 trifluoroacetate disrupts the tumor-promoting interactions between CAFs and tumor cells, potentially impeding tumor growth and progression.

Formula: C₄₁H₅₇F₂N₁₁O₉•(C₂HF₃O₂)x

Purity: Min. 95%

Ref: 3D-BF183978