CAS 2375-03-3

Methylprednisolone sodium succinate

Description:

Methylprednisolone sodium succinate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is a white to off-white crystalline powder that is soluble in water, making it suitable for parenteral administration. The compound is a derivative of prednisolone, modified to enhance its solubility and bioavailability. Methylprednisolone sodium succinate is commonly used in clinical settings to treat a variety of conditions, including allergic reactions, autoimmune disorders, and inflammatory diseases. Its mechanism of action involves the modulation of gene expression, leading to decreased production of pro-inflammatory cytokines and inhibition of immune cell function. The substance is typically administered intravenously or intramuscularly, and its effects can be observed relatively quickly, making it effective for acute conditions. As with other corticosteroids, potential side effects may include increased susceptibility to infections, fluid retention, and alterations in glucose metabolism, necessitating careful monitoring during treatment.

Formula: C₂₆H₃₄O₈·Na

InChI: InChI=1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1

InChI key: InChIKey=WOARBZBOZOGFGA-SGJOWKDISA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(COC(CCC(O)=O)=O)=O)O)[H].[Na]

Synonyms:

• 6-Methylprednisolone sodium succinate
• 6-alpha-Methyl Prednisolone Sodium Succinate
• 6alpha-Methylprednisolone sodium succinate
• 6α-Methylprednisolone 21-sodium hemisuccinate
• 6α-Methylprednisolone 21-sodium succinate
• 6α-Methylprednisolone sodium hemisuccinate
• 6α-Methylprednisolone sodium succinate
• 6α-Methylpregnisolone 21-sodium succinate
• Methyl prednisolone sodium succinate
• Methylprednisolone Sodium Succinate
• Methylprednisolone hemisuccinate sodium
• Methylprednisolone succinate sodium
• Metypred
• NSC 48989
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(hydrogen succinate), monosodium salt
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(hydrogen succinate), sodium salt
• Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-, monosodium salt, (6α,11β)-
• Sodium 4-{[(6Alpha,11Beta)-11,17-Dihydroxy-6-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl]Oxy}-4-Oxobutanoate
• Sodium methylprednisolone succinate
• Solu-Medrol
• Solu-Medrone
• Succinic acid, 21-monoester with 11β,17,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione, monosodium salt
• U 9088
• Urbason Solubile

6α-Methylprednisolone 21-hemisuccinate (sodium salt)

CAS: 2375-03-3

Formula: C₂₆H₃₄NaO₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 497.5331

Ref: IN-DA00I4LE

6α-Methylprednisolone 21-hemisuccinate sodium salt

CAS: 2375-03-3

Formula: C₂₆H₃₃O₈Na

Molecular weight: 496.53

Ref: 7W-GK7601

6α-Methylprednisolone 21-hemisuccinate sodium salt

CAS: 2375-03-3

6α-Methylprednisolone 21-hemisuccinate sodium salt

Purity: ≥98%

Molecular weight: 496.53g/mol

Ref: 54-BUP15033

6α-Methylprednisolone 21-hemisuccinate sodium salt

CAS: 2375-03-3

6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.

Formula: C₂₆H₃₃NaO₈

Purity: 99.65%

Color and Shape: Lyophilized Powder

Molecular weight: 496.53

Ref: TM-T0294

Methylprednisolone Hydrogen Succinate Sodium Salt

Controlled Product

CAS: 2375-03-3

Formula: C₂₆H₃₃O₈·Na

Color and Shape: Neat

Molecular weight: 496.53

Ref: 86-MM0192.00

6α-Methylprednisolone 21-Hemisuccinate Sodium Salt

Controlled Product

CAS: 2375-03-3

Applications 6α-Methylprednisolone 21-Hemisuccinate is a glucocorticosteroid used in anti-inflammatory medication in the treatment of spinal cord injuries.
References Kim, S. et al.: Intern. Medicin., 49,1119 (2010); Chvatal, S. et al.: Biomat., 29, 1967 (2008);

Formula: C₂₆H₃₃O₈·Na

Color and Shape: Neat

Molecular weight: 496.53

Ref: TR-M326725

(6α,11β)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-Pregna-1,4-diene-3,20-dione monosodium salt

Controlled Product

CAS: 2375-03-3

(6alpha,11beta)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-Pregna-1,4-diene-3,20-dione monosodium salt is a steroidal anti-inflammatory drug. It has been studied in a low dose group of patients with rheumatoid arthritis and found to be effective in reducing the signs and symptoms of the disease. The drug is metabolized to methylprednisolone, which inhibits inflammation and pain by blocking the production of prostaglandins. (6alpha,11beta)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl Pregna 1,4 diene 3,20 dione monosodium salt has minimal toxicity and does not cause gastric irritation or ulcers. This compound also does not affect immune system function or cause

Formula: C₂₆H₃₃NaO₈

Purity: Min. 95%

Molecular weight: 496.53 g/mol

Ref: 3D-FM37266