CAS 2377167-56-9

1,2-Pyrrolidinedicarboxamide, N1-(6-chloro-3-pyridinyl)-N2-[(2,4-dichlorophenyl)methyl]-5-oxo-, (2S)-

Description:

1,2-Pyrrolidinedicarboxamide, N1-(6-chloro-3-pyridinyl)-N2-[(2,4-dichlorophenyl)methyl]-5-oxo-, (2S)- is a synthetic organic compound characterized by its complex structure, which includes a pyrrolidine ring and multiple functional groups such as amides and chlorinated aromatic systems. This compound typically exhibits properties associated with its amide functional groups, including potential solubility in polar solvents and the ability to engage in hydrogen bonding. The presence of chlorine substituents on the aromatic rings may enhance its biological activity and lipophilicity, influencing its interactions with biological targets. The stereochemistry indicated by the (2S) designation suggests specific spatial arrangements of atoms, which can significantly affect the compound's pharmacological properties. As a result, this compound may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. Its unique combination of structural features may also contribute to its stability and reactivity under various conditions, making it a subject of study in both synthetic and applied chemistry contexts.

Formula: C₁₈H₁₅Cl₃N₄O₃

Synonyms:

• 1,2-Pyrrolidinedicarboxamide, N1-(6-chloro-3-pyridinyl)-N2-[(2,4-dichlorophenyl)methyl]-5-oxo-, (2S)-
• HEI3090

HEI3090

CAS: 2377167-56-9

HEI3090 is an activator of the P2X7R receptor. This compound enhances the production of IL-18 by stimulating dendritic cells that express P2X7R, which in turn promotes the production of IFN-γ by natural killer cells and CD4T cells within tumors, triggering a sustained anti-tumor response. Additionally, HEI3090 can be used to improve the efficacy of αPD-1 therapy in non-small cell lung cancer (NSCLC).

Formula: C₁₈H₁₅Cl₃N₄O₃

Color and Shape: Solid

Molecular weight: 441.70

Ref: TM-T89862