Amyloid Beta-Protein (10-35), with the CAS number 237753-66-1, is a peptide fragment derived from the larger amyloid precursor protein (APP). This specific fragment consists of amino acids 10 to 35 of the full-length amyloid beta peptide, which is implicated in the pathogenesis of Alzheimer's disease. Characteristically, this peptide is hydrophilic and can aggregate to form oligomers and fibrils, which are associated with neurotoxicity and the formation of amyloid plaques in the brains of Alzheimer's patients. The aggregation process is influenced by factors such as pH, temperature, and the presence of metal ions. Additionally, Amyloid Beta-Protein (10-35) can interact with various cellular receptors and proteins, potentially disrupting synaptic function and contributing to neurodegeneration. Its study is crucial for understanding the molecular mechanisms underlying Alzheimer's disease and for developing therapeutic strategies aimed at preventing or reversing amyloid aggregation. Overall, this peptide serves as a significant model for research into amyloid-related pathologies.

Amyloid Beta-Protein (10-35)

237753-66-1: Amyloid Beta-Protein (10-35), with the CAS number 237753-66-1, is a peptide fragment derived from the larger amyloid precursor protein (APP). This specific fragment consists of amino acids 10 to 35 of the full-length amyloid beta peptide, which is implicated in the pathogenesis of Alzheimer's disease. Characteristically, this peptide is hydrophilic and can aggregate to form oligomers and fibrils, which are associated with neurotoxicity and the formation of amyloid plaques in the brains of Alzheimer's patients. The aggregation process is influenced by factors such as pH, temperature, and the presence of metal ions. Additionally, Amyloid Beta-Protein (10-35) can interact with various cellular receptors and proteins, potentially disrupting synaptic function and contributing to neurodegeneration. Its study is crucial for understanding the molecular mechanisms underlying Alzheimer's disease and for developing therapeutic strategies aimed at preventing or reversing amyloid aggregation. Overall, this peptide serves as a significant model for research into amyloid-related pathologies.

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CAS 237753-66-1

Amyloid Beta-Protein (10-35)

Amyloid beta-Protein (10-35) trifluoroacetate salt

Ref: 3D-FA109820