CAS 23779-97-7

4-Chloro-8-(trifluoromethyl)quinoline

Description:

4-Chloro-8-(trifluoromethyl)quinoline is a chemical compound belonging to the quinoline family, characterized by a bicyclic structure that includes a benzene ring fused to a pyridine ring. This compound features a chlorine atom at the 4-position and a trifluoromethyl group at the 8-position, which significantly influences its chemical properties and reactivity. The presence of the trifluoromethyl group enhances lipophilicity and can affect the compound's biological activity, making it of interest in medicinal chemistry. 4-Chloro-8-(trifluoromethyl)quinoline is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. Its unique structure allows for potential applications in pharmaceuticals, agrochemicals, and materials science. Additionally, the compound may exhibit specific biological activities, including antimicrobial or antitumor properties, which are often investigated in drug development. Safety and handling precautions should be observed, as with many halogenated compounds, due to potential toxicity and environmental impact.

Formula: C₁₀H₅ClF₃N

InChI: InChI=1S/C10H5ClF3N/c11-8-4-5-15-9-6(8)2-1-3-7(9)10(12,13)14/h1-5H

InChI key: InChIKey=LINGICLAECZKAW-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1C2=C(C(Cl)=CC=N2)C=CC1

Synonyms:

• 5,5,5-Trifluoronorvaline
• Quinoline, 4-chloro-8-(trifluoromethyl)-
• 4-Chloro-8-(trifluoromethyl)quinoline

4-Chloro-8-(trifluoromethyl)quinoline

CAS: 23779-97-7

Formula: C₁₀H₅ClF₃N

Purity: 98%

Color and Shape: Solid

Molecular weight: 231.6016

Ref: IN-DA00BCLC

4-Chloro-8-(trifluoromethyl)quinoline

CAS: 23779-97-7

4-Chloro-8-(trifluoromethyl)quinoline

Purity: 98%

Molecular weight: 231.60g/mol

Ref: 54-PC2075N

4-Chloro-8-(trifluoromethyl)quinoline

CAS: 23779-97-7

Formula: C₁₀H₅ClF₃N

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 231.60

Ref: 3B-C3067

4-Chloro-8-(trifluoromethyl)quinoline

CAS: 23779-97-7

Formula: C₁₀H₅ClF₃N

Purity: 98%

Color and Shape: Solid

Molecular weight: 231.6

Ref: 10-F004562

4-Chloro-8-(trifluoromethyl)quinoline

Controlled Product

CAS: 23779-97-7

Applications 4-Chloro-8-(trifluoromethyl)quinoline is used as a reagent for the potent CRTh2 (DP2) receptor antagonists discovery which is used for treatment of asthma, allergic rhinitis and other inflammatory diseases.
References Birkinshaw, T.N., et al.: Bioorg. Med. Chem. Lett., 16, 4287 (2006)

Formula: C₁₀H₅ClF₃N

Color and Shape: Neat

Molecular weight: 231.6

Ref: TR-C422050

4-Chloro-8-(trifluoromethyl)quinoline

CAS: 23779-97-7

4-Chloro-8-(trifluoromethyl)quinoline is a functionalized organic compound that is used as an antimicrobial agent. It has been shown to inhibit the growth of bacteria by reacting with nucleophilic sites on the surface of metal, thereby preventing the formation of corrosive substances. It also has properties that make it an excellent corrosion inhibitor. 4-Chloro-8-(trifluoromethyl)quinoline binds strongly to amines and acidic sites on metal surfaces, which are common features in bacterial cell walls, leading to its antimicrobial activity. This compound can be used as a cross-coupling agent in chemical reactions and electrochemical methods.

Purity: Min. 95%

Ref: 3D-FC42096