Mal-amido-PEG12-acid is a chemical compound characterized by its structure, which includes a polyethylene glycol (PEG) chain with a malemide functional group and a carboxylic acid group. The PEG segment typically imparts hydrophilicity, enhancing solubility in aqueous environments, while the malemide group is known for its reactivity, particularly in conjugation reactions with nucleophiles, making it useful in bioconjugation applications. The presence of the carboxylic acid group allows for further functionalization and can facilitate interactions with other molecules, such as proteins or drugs. This compound is often utilized in biochemistry and materials science for applications such as drug delivery systems, where its ability to form stable conjugates can improve the pharmacokinetics and bioavailability of therapeutic agents. Additionally, the PEG component can help reduce immunogenicity and increase circulation time in biological systems. Overall, Mal-amido-PEG12-acid serves as a versatile building block in the development of advanced biomaterials and therapeutic formulations.

Mal-amido-PEG12-acid

2378428-27-2: Mal-amido-PEG12-acid is a chemical compound characterized by its structure, which includes a polyethylene glycol (PEG) chain with a malemide functional group and a carboxylic acid group. The PEG segment typically imparts hydrophilicity, enhancing solubility in aqueous environments, while the malemide group is known for its reactivity, particularly in conjugation reactions with nucleophiles, making it useful in bioconjugation applications. The presence of the carboxylic acid group allows for further functionalization and can facilitate interactions with other molecules, such as proteins or drugs. This compound is often utilized in biochemistry and materials science for applications such as drug delivery systems, where its ability to form stable conjugates can improve the pharmacokinetics and bioavailability of therapeutic agents. Additionally, the PEG component can help reduce immunogenicity and increase circulation time in biological systems. Overall, Mal-amido-PEG12-acid serves as a versatile building block in the development of advanced biomaterials and therapeutic formulations.

Mal-amido-PEG12-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

CAS 2378428-27-2

Mal-amido-PEG12-acid

Mal-amido-PEG12-acid

Ref: TM-T18236

Mal-amido-PEG12-acid

Ref: 10-F554828