CAS 2379-57-9: DNQX

Description: DNQX, or 2,3-dihydroxy-6-nitro-7-sulfamoylquinoxaline, is a synthetic compound primarily recognized for its role as a selective antagonist of the AMPA and kainate subtypes of glutamate receptors in the central nervous system. This compound is often utilized in neuropharmacological research to study excitatory neurotransmission and its implications in various neurological disorders. DNQX is characterized by its ability to inhibit synaptic transmission mediated by glutamate, thereby providing insights into synaptic plasticity and neurotoxicity. It is typically administered in laboratory settings and is known for its relatively high potency and specificity. The compound is soluble in certain organic solvents, which facilitates its use in experimental applications. However, like many pharmacological agents, DNQX must be handled with care due to potential toxicity and the need for precise dosing in research contexts. Overall, DNQX serves as a valuable tool in the exploration of glutamatergic signaling pathways and their roles in health and disease.

Formula: C₈H₄N₄O₆

InChI: InChI=1S/C8H4N4O6/c13-7-8(14)10-4-2-6(12(17)18)5(11(15)16)1-3(4)9-7/h1-2H,(H,9,13)(H,10,14)

InChI key: InChIKey=RWVIMCIPOAXUDG-UHFFFAOYSA-N

SMILES: O=C1NC=2C=C(C(=CC2NC1=O)N(=O)=O)N(=O)=O

Synonyms:

• 1,4-Dihydro-6,7-dinitro-2,3-quinoxalinedione
• 2,3-Quinoxalinediol, 6,7-Dinitro-
• 2,3-Quinoxalinedione, 1,4-dihydro-6,7-dinitro-
• 6,7-Dinitro-2,3-Quinoxalinediol
• 6,7-Dinitro-2,3-dihydroxyquinoxaline
• 6,7-Dinitroquinoxaline-2,3-(1H,4H)-dione
• 6,7-Dinitroquinoxaline-2,3-Diol
• Fg 9041
• 6,7-Dinitro-1,4-dihydroquinoxaline-2,3-dione

DNQX

CAS: 2379-57-9

• Formula: C₈H₄N₄O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 252.1406

DNQX

CAS: 2379-57-9

• Formula: C₈H₄N₄O₆
• Molecular weight: 252.14

6,7-Dinitro-1,4-Dihydroquinoxaline-2,3-Dione

CAS: 2379-57-9

• Purity: 98%
• Molecular weight: 252.14g/mol

DNQX

CAS: 2379-57-9

• Formula: C₈H₄N₄O₆
• Purity: >95.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 252.14

DNQX

CAS: 2379-57-9

DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 …

• Formula: C₈H₄N₄O₆
• Purity: 97.15% - 99.10%
• Color and Shape: Off-White Powder With A Yellow Tinge
• Molecular weight: 252.14

6,7-Dinitroquinoxaline-2,3-dione

CAS: 2379-57-9

Stability Store in freezer at -20°C Applications Potent competitive non-NMDA glutamate receptor antagonist. References Honore, …

• Formula: C₈H₄N₄O₆
• Color and Shape: Neat
• Molecular weight: 252.14

DNQX

CAS: 2379-57-9

AMPA/ kainate receptor antagonist

• Formula: C₈H₄N₄O₆
• Purity: Min. 95%
• Molecular weight: 252.14 g/mol

DNQX Disodium salt

CAS: 2379-57-9

• Purity: 98%
• Molecular weight: 296.106